Comment · Wed, August 6, 2025 · ND Owner
⚠️ NEW PRODUCTS ALERT | Cyatherm Capsules, Lucidimax Capsules, Peruvian Black Maca Powder, Mushroom Magic Powder, Mushroom Magic Advanced Powder, & TUDCA Capsules⚠️
Original post in this thread
NDSocialMedia · 74 points
Support your metabolism with new Cyatherm Capsules! Expertly crafted, Cyatherm combines science-backed botanicals including CaloriBurn, C3G, Black Ginger, Ecklonia cava, Rauwolscine, Piperine and Chromium to energize your day and help you maintain healthy metabolic function. Enhanced with piperine for superior absorption and third-party tested for quality, Cyatherm is your new everyday ally for energy, thermogenesis, and overall metabolic wellness.
Experience the full-spectrum power of Reishi with Lucidimax Optimized Reishi! This advanced formula brings together polysaccharide-rich fruiting bodies, potent spore triterpenes, and high ganoderic acid extracts for robust immune support, relaxation, and daily balance. Lucidimax sets a new standard for Reishi supplemen…
What they were answering
AAAUUUUAUAUAUUAUA · 2 points
This is super sick! I know you guys are already doing a lot and doing more stuff means more work, but i am curious as to why you guys dont make this into a bigger deal/ make an announcement. Obviously im asking this partially out of my selfish desire to know things that seem to be at the forefront for "free", but this is also probably a good marketing opportunity for you guys, for example, when you get the chromatogram readings, rather than sitting on them for a little while and linking them like this in reddit to prove something when needed, why not be proactive with it? Even if it might not be the best marketing for an "average" consumer since they dont really know what it is or means, i definitely think it could convince some people who are on the edge of being regular customers to become more frequent buyers since its reconfirming the reason why they bought from you in the first place, which is that they believe that ND is the best source to buy from. Basically, i think it could increase the conversion from amazon buyer to redditor (not ment as an insult, for once!). And for the people who are already here, itd be a nice little announcement, it might spark some discussion, maybe some renewed interest in whatever you guys have tested and on top of that it gives us a little update. Dont get me wrong, compared to average supplement company you guys are definitely doing both t…
u/MisterYouAreSoDumb · ND Owner
I know you guys are already doing a lot and doing more stuff means more work, but i am curious as to why you guys dont make this into a bigger deal/ make an announcement. Obviously im asking this partially out of my selfish desire to know things that seem to be at the forefront for "free", but this is also probably a good marketing opportunity for you guys, for example, when you get the chromatogram readings, rather than sitting on them for a little while and linking them like this in reddit to prove something when needed, why not be proactive with it?
Frankly, that's mostly because we are so busy. We are doing too many things at once. Because there are too many pokers in the fire, we really don't focus on talking up all the stuff we are doing for marketing purposes. I do get excited and talk about things that are happening here on Reddit sometimes. However, as you said, it's not ideal. We should do a better job of making our science efforts more apparent to everyone.
Yeah lol... the standardisation is a bit questionable to say the least. I will say though, best case scenario, they are trying to obscure what the bioactives are so that no one else knows what to standardise for without doing the research themselves, which is expensive, in some ways that gives them the protection a patent on a compound gives, kind of, giving them a bigger share of the market. And irrespective of this shady stuff, unless there is some sort of fraud going on in, for example the small schizophrenia trial they did with amyloban, where they used something that they dont sell or sell a watered down version of what is used in the trials, there is something very interesting going on, even though it was a small trial with 6 people in the experimental group and 4 in the placebo, all of the people in the experimental group improved! Not only did they improve, they have treatment resistant schizophrenia and are on an ungodly amount of medication, but they went from being non functional to becoming at least semi functional, i think a few of them started working again. There is also anecdotal evidence of severely ill people being able to reduce their medication due to this. So unless there is some sort of fraud going on with whats used in science vs whats sold or its spiked with the limitless drug, those amylobans seem to be doing something!
For sure the standardization is BS. That doesn't mean it doesn't contain anything, though. It might actually work and have beneficial compounds. However, proper standardization and the validated lab testing to back it up is kind of my main focus, so doing BS like they are doing sets off all my alarms. You did make me curious about the study, though.
https://www.sciencedirect.com/science/article/abs/pii/S2186495014000145
Amyloban®3399—a product made of amycenon, a standardized extract of H. erinaceum containing hericenones and amyloban—is currently being tested for safety as a health food supplement.
Okay, so now there is another word they made up in there: amycenon. So it is Amyloban, made from amycenon, standardized to amyloban (which supposedly contains some amounts of hericenones). Cool... Also, only 10 participants? That's a crazy low sample size. The Alzheimer's study on our Erinamax recruited 68 participants, with 41 completing the study.
https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2020.00155/full
The other study on Erinamax for hearing loss in the elderly has 80 participants.
https://www.sciencedirect.com/science/article/pii/S1756464622002900
In their other study, they seem to get a bit more committal for what the standardization is.
https://onlinelibrary.wiley.com/doi/full/10.1002/npr2.12480
The main components of amyloban are hericenones extracted from the mushroom Hericium erinaceus.
So they say the main components are hericenones, but don't give an actual set content. If you notice in the study on Erinamax, it's clear that it contains 5mg/g, or 0.5%, of erinacine A. We don't say: "Standardized to erinamax, which primarily consists of erinacines." That would be silly. We will see what we find for hericenones and hericenes when it gets here. I would assume I should have some data in a few weeks, depending on when my lab can get to it.
Ohh, and I found the other samples where we found erinacine A. It was from the supplier behind this study.
That's from MycoMedica, with a retail product name of Goba. Here were those results.
Goba erinacine A assay chromatogram
So we actually found erinacine A in there, but it was only at 0.158%. This is the closest retail product to our Erinamax, but still far below our concentration. They don't even sell it anymore. They moved to just a fruiting body product, and got rid of the erinacine A one. They were the closest to matching us on the mycelium side, though. Then we also bought a product from MycoMedica that claimed 1.5mg erinacine A per capsule. Here are those results.
MycoMedicca erinacine A assay chromatogram
So they claim 1.5mg erinacine A per capsule, but we only found 0.019mg per capsule. Massive fail for label claim.
i think there was a thread a month or so ago where the argument was made that the bioavailability of the actives was greatly reduced when its not extracted, basically it would be great to have a more "guaranteed" bioavailability.
I didn't see that thread at the time, because I have been staying off Reddit for the most part, but that's not true. People are fundamentally misunderstanding the bioavailability of Erinamax. The idea you need to extract it, or your body can't absorb it, isn't correct. For one, the mycelium of lion's mane has much easier to digest cell walls than the fruiting bodies. Moreover, lion's mane in general has much more digestible cell walls than other mushrooms like reishi and chaga. Those absolutely need to have post processing to break down. However, lion's mane is not like that. The chitin-cellulose fibers in lion's mane are easily digestible in the human GI tract. Even so, our Erinamax is lyophilized in the drying process. This sublimates the water in the mycelium, which creates millions of holes in the fungal structure as it dries. This physically breaks apart the cell walls of the mycelium in the drying process. So no extraction is needed.
We've also made extracts of Erinamax, and I have tried them a bunch. There is no difference in effects when accounting for erinacine A concentration. Sure, if you concentrate it and get more erinacine A per dose, then you feel it more. However, you can just take a higher dose of Erinamax for the same effect, without the added cost of the extraction. We will offer an extract of erinacine A lion's mane at some point, but the cost is the issue. If we can get the cost of the raw material down, then we can make that work. However, it is not going to improve bioavailability the way people think. In fact, something is lost in the process. I've taken pure erinacine A myself, and it doesn't feel the same. There is a lot more to Erinamax than just the erinacine A content. There is also erinacine C in Erinamax, along with other things like polysaccharides that all go into the effect profile. So sometimes extracting things make them worse. It has to be a data-driven approach, and the two double blinded human clinical studies we have on Erinamax use non-extracted material.