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Comment · Wed, August 6, 2025 · ND Owner

⚠️ NEW PRODUCTS ALERT | Cyatherm Capsules, Lucidimax Capsules, Peruvian Black Maca Powder, Mushroom Magic Powder, Mushroom Magic Advanced Powder, & TUDCA Capsules⚠️

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NDSocialMedia · 74 points

NEW PRODUCTS ALERT | Cyatherm Capsules, Lucidimax Capsules, Peruvian Black Maca Powder, Mushroom Magic Powder, Mushroom Magic Advanced Powder, & TUDCA Capsules

Cyatherm

Support your metabolism with new Cyatherm Capsules! Expertly crafted, Cyatherm combines science-backed botanicals including CaloriBurn, C3G, Black Ginger, Ecklonia cava, Rauwolscine, Piperine and Chromium to energize your day and help you maintain healthy metabolic function. Enhanced with piperine for superior absorption and third-party tested for quality, Cyatherm is your new everyday ally for energy, thermogenesis, and overall metabolic wellness.

Lucidimax

Experience the full-spectrum power of Reishi with Lucidimax Optimized Reishi! This advanced formula brings together polysaccharide-rich fruiting bodies, potent spore triterpenes, and high ganoderic acid extracts for robust immune support, relaxation, and daily balance. Lucidimax sets a new standard for Reishi supplemen…

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lewanay · 3 points

The effects of Berberine are similar to metformin. Do you worry about the exercise blunting effects like with Merformin? I had to stop taking it for that reason

u/MisterYouAreSoDumb · ND Owner

How did you measure its effects on exercise? Did you see significant issues there? The main difference between metformin and berberine in this area are multifold. One, metformin's negative effects are linear in a dose/response sense. This means that the side effects are consistent at all doses, and just go up as the dose gets higher. Berberine has a biphasic dose/response curve. This means that while higher doses of berberine can inhibit muscle growth, more reasonable ones should not. In fact, lower doses of berberine can have a positive effect there.

Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis

So it depends on what dose you are taking of berberine. I take our Berbelean every day in the morning, and just take it once a day. That works well for me. I am also taking some other muscle supporting supplements like epicatechin, so I don't see any issues with exercise and muscle growth. However, if I was taking Berbelean multiple times a day, or taking regular berberine 3X per day like some people do, that might be a different story.

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