Skip to content

Comment · Mon, December 31, 2012

MDMA Supplementation

Original post in this thread

MisterYouAreSoDumb · 205 points

Ok, I did promise that I would make another post regarding supplementation to mitigate MDMA induced neurotoxicity. I have just been putting it off. Since my last post, I have gathered more information regarding my theory about MDA metabolism being the main cause of MDMA's neurotoxic effects. I will try to not get into that in this post, and keep this mostly about supplementation. As seems to be the norm with me, this may be long winded. Obviously everything I put on this list is not necessary. I will be placing supplements into different categories, with reasonings and references. I will let you decide which ones will be a part of your regimen.

_______________________________________________________
Essential Supplements:

* Alpha Lipoic Acid- This is one that everyone should be taking. It is a powerful antioxidant that scavenges reactive oxygen and nitrogen species. It also has a nice benefit of regenerating other vitamins, like C, after redox cycling. It exists in two enantiomers, R-ALA and S-ALA. R-ALA is the biologically active isomer that we are looking for. Most supplements a…

What they were answering

bannana · 1 points

Tried some piracetam and had horrible headaches every time. Could have been the quality but I did read it's one of the side effects. I only did it for a few days and just a tiny bit at a time so I don't think I did enough to alter my situation.

u/MisterYouAreSoDumb

That usually means that you are deficient in choline. Try a choline precursor like soy lecithin, CDP choline, or Alpha GPC, and see how that works.

Other MYASD lines in this threadshowing 40 of 107

Related in the archive

Commentr/NootropicsAug 10, 2016

Why should I spend additional money on suppliers that charge more than powdercity?

Have you actually even looked at the prices, or are you just assuming PC is lower? We are actually lower on certain things, and the exact same on others. In fact, we are half price on some things. Actually look at the pr

27NoopeptPiracetamAniracetamModafinil
Commentr/NootropicsDepotJun 12, 2020

New products in the pipeline?

Replying to bluMidge · Omg, You are the coolest, most knowledgeable dude anywhere. And anywhere can encompass a lot of places.lol Thank you so much again for all you and your company brings to the table

If I were taking amphetamine every day, I would absolutely take a few things. * A good magnesium (glycinate if you take at night, or our Micromag for the day) * A good alpha lipoic acid (Na-R-ALA or our OptimALA) * ALCA

15PiracetamUridineAlpha-GPCMagnesium
Commentr/NootropicsMar 17, 2013

I'm am about to take my first dose of nootropics. Pira, Ani, Noopept, Alpha-GPC.

Replying to michaelodeon · First thing I'm going to say is: WHOA. This stuff is the real deal. I honestly did not expect anything to happen which is why I just stacked everything together. A bunch of my frie

Haha, you just jumped right in there! Now you have the task of isolating which ones were mostly responsible, and finding your ideal dose. I'd start with piracetam, then work your way to the stronger ones. Piracetam's eff

9NoopeptPiracetamAlpha-GPCRacetams
Commentr/NootropicsDepotDec 3, 2022

Anybody Have a Clue What Ebelin Lactone’s 5-HT2A binding affinity is?

Replying to PineyTinecones · What is considered a medium and high dose of Alpha-GPC? I’m trying to dial in my choline intake alongside some other stuff like Phenylpiracetam and some ache-i’s I’m taking for va

I'd say 250mg is a medium dose. Any over that is a high dose, in my opinion.

6PiracetamPhenylpiracetamAlpha-GPCRacetams
Commentr/NootropicsFeb 26, 2014

Nuance: CDP Choline vs Alpha GPC

Replying to Maxwell_V · PS: I thought of a good analogy. Many people walk into a museum with modern art, and it's all just random-looking squares and bizarre shapes. But someone with a practiced eye can e

Well that is going to take time. We can read all the studies we want. However, knowing how those mechanisms feel is totally different. A better analogy is wine. Most people taste a wine and do not notice the subtle nuan

6PiracetamPhenylpiracetamColuracetamAlpha-GPC
Commentr/NootropicsMar 18, 2013

Friend gave me some piracetam and choline powder - feel a difference but which is taking the effect?

>I've read piracetam is **relatively** weak That's the key here, relativity. It's "weak" in comparison to other racetams that are active at much lower doses. That does not mean that the effects are unnoticeable. I notic

6PiracetamAlpha-GPCRacetams