Comment · Mon, December 31, 2012
MDMA Supplementation
Original post in this thread
MisterYouAreSoDumb · 205 points
Ok, I did promise that I would make another post regarding supplementation to mitigate MDMA induced neurotoxicity. I have just been putting it off. Since my last post, I have gathered more information regarding my theory about MDA metabolism being the main cause of MDMA's neurotoxic effects. I will try to not get into that in this post, and keep this mostly about supplementation. As seems to be the norm with me, this may be long winded. Obviously everything I put on this list is not necessary. I will be placing supplements into different categories, with reasonings and references. I will let you decide which ones will be a part of your regimen.
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Essential Supplements:
* Alpha Lipoic Acid- This is one that everyone should be taking. It is a powerful antioxidant that scavenges reactive oxygen and nitrogen species. It also has a nice benefit of regenerating other vitamins, like C, after redox cycling. It exists in two enantiomers, R-ALA and S-ALA. R-ALA is the biologically active isomer that we are looking for. Most supplements a…
What they were answering
Carl_Sagacity · 2 points
I had saved your old post so I could get the supplements I needed before New Years. I was just checking back on it now and coincidentally you updated just in time! Thanks for doing all of this research.
EDIT: Also, it seems that the magnesium supplements can cause stomach problems/diarrhea. Obviously I should have bought them sooner so I could test them out but alas I did not. Would you recommend still taking it, maybe in a smaller dosage or should the Alpha Lipoic Acid/Emergen-C/Grape Seed Extract be enough? I really don't want to be shitting my pants during a rave, but I do like my neurons...
u/MisterYouAreSoDumb
What type of magnesium did you get?