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Comment · Mon, December 31, 2012

MDMA Supplementation

Original post in this thread

MisterYouAreSoDumb · 205 points

Ok, I did promise that I would make another post regarding supplementation to mitigate MDMA induced neurotoxicity. I have just been putting it off. Since my last post, I have gathered more information regarding my theory about MDA metabolism being the main cause of MDMA's neurotoxic effects. I will try to not get into that in this post, and keep this mostly about supplementation. As seems to be the norm with me, this may be long winded. Obviously everything I put on this list is not necessary. I will be placing supplements into different categories, with reasonings and references. I will let you decide which ones will be a part of your regimen.

_______________________________________________________
Essential Supplements:

* Alpha Lipoic Acid- This is one that everyone should be taking. It is a powerful antioxidant that scavenges reactive oxygen and nitrogen species. It also has a nice benefit of regenerating other vitamins, like C, after redox cycling. It exists in two enantiomers, R-ALA and S-ALA. R-ALA is the biologically active isomer that we are looking for. Most supplements a…

What they were answering

bannana · 1 points

I eat a lot of eggs, though.

I must be extremely deficient then, I eat 4 whole eggs per day and have for a few years.

Do you view /r/Nootropics ever?

No I haven't but will check it out. Thanks for the information/advice, I had resigned myself to not being able to experience mdma again but I'm finding myself really missing it lately. It's been about 5yrs since I've had a positive experience and I know it would do me some good at this point since I've been experiencing some lingering ennui/depression/existential crises type moods for the last year and mdma has worked wonders previously.

u/MisterYouAreSoDumb

I guarantee that nootropics can help. If not piracetam, there are others that people respond to. Those that do not respond to piracetam seem to respond to aniracetam.

As far as the choline thing goes, it varies so much from person to person. I've seen people that need a ton of choline supplementation with their racetams. Then there are people like me that do not need any. Nobody knows for sure why that is. The interactions are so complex, that it could be a number of different things.

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