Comment · Thu, January 31, 2013
MDMA Supplementation
Original post in this thread
MisterYouAreSoDumb · 205 points
Ok, I did promise that I would make another post regarding supplementation to mitigate MDMA induced neurotoxicity. I have just been putting it off. Since my last post, I have gathered more information regarding my theory about MDA metabolism being the main cause of MDMA's neurotoxic effects. I will try to not get into that in this post, and keep this mostly about supplementation. As seems to be the norm with me, this may be long winded. Obviously everything I put on this list is not necessary. I will be placing supplements into different categories, with reasonings and references. I will let you decide which ones will be a part of your regimen.
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Essential Supplements:
* Alpha Lipoic Acid- This is one that everyone should be taking. It is a powerful antioxidant that scavenges reactive oxygen and nitrogen species. It also has a nice benefit of regenerating other vitamins, like C, after redox cycling. It exists in two enantiomers, R-ALA and S-ALA. R-ALA is the biologically active isomer that we are looking for. Most supplements a…
What they were answering
AskQGetA · 1 points
Does the sheer volume of supplement pills pose a problem when taking them "during", considering the lack of appetite from MDMA and the capsule size of some of these supplements (especially magnesium)? I can imagine one's stomach protesting, even to the point of gagging, when trying to swallow them. Has that ever been an issue for you, or do you have workarounds, such as crushing the (less disgusting) supplements into a fine powder and mixing them with water?
Also, how do you present the concept of supplementing to people who might be skeptical about it? I don't expect that anyone will be dismissive of the supplements' protective properties, but I can foresee that some people might be put off by (or even scared of) taking 7 pills when they're 2 hours into a roll. Without giving them a crash course on biochemistry, what's the best way to deal with this in your experience?
u/MisterYouAreSoDumb
I never have any problems with taking pills, nor do I have any issue with appetite or ingesting food/drink while on MDMA.
Who would be skeptical about it? If they are already willing to take MDMA, it's not too hard to explain why they should supplement to protect themselves. I just explain what each supplement is for and why we should take it.