Comment · Mon, December 31, 2012
MDMA Supplementation
Original post in this thread
MisterYouAreSoDumb · 205 points
Ok, I did promise that I would make another post regarding supplementation to mitigate MDMA induced neurotoxicity. I have just been putting it off. Since my last post, I have gathered more information regarding my theory about MDA metabolism being the main cause of MDMA's neurotoxic effects. I will try to not get into that in this post, and keep this mostly about supplementation. As seems to be the norm with me, this may be long winded. Obviously everything I put on this list is not necessary. I will be placing supplements into different categories, with reasonings and references. I will let you decide which ones will be a part of your regimen.
_______________________________________________________
Essential Supplements:
* Alpha Lipoic Acid- This is one that everyone should be taking. It is a powerful antioxidant that scavenges reactive oxygen and nitrogen species. It also has a nice benefit of regenerating other vitamins, like C, after redox cycling. It exists in two enantiomers, R-ALA and S-ALA. R-ALA is the biologically active isomer that we are looking for. Most supplements a…
What they were answering
Carl_Sagacity · 1 points
I decided against it. I have a sensitive digestive track and would rather not risk spending the night in the bathroom.
u/MisterYouAreSoDumb
I understand your concern, but I would highly suggest it. Excitotoxicity leads to tolerance and things like jaw clenching. If bad enough, it can also cause neuronal death. Magnesium glycinate never causes GI tract irritation. It's up to you, just be as safe as you can.