Comment · Tue, June 7, 2022
MDMA Supplementation
Original post in this thread
MisterYouAreSoDumb · 205 points
Ok, I did promise that I would make another post regarding supplementation to mitigate MDMA induced neurotoxicity. I have just been putting it off. Since my last post, I have gathered more information regarding my theory about MDA metabolism being the main cause of MDMA's neurotoxic effects. I will try to not get into that in this post, and keep this mostly about supplementation. As seems to be the norm with me, this may be long winded. Obviously everything I put on this list is not necessary. I will be placing supplements into different categories, with reasonings and references. I will let you decide which ones will be a part of your regimen.
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Essential Supplements:
* Alpha Lipoic Acid- This is one that everyone should be taking. It is a powerful antioxidant that scavenges reactive oxygen and nitrogen species. It also has a nice benefit of regenerating other vitamins, like C, after redox cycling. It exists in two enantiomers, R-ALA and S-ALA. R-ALA is the biologically active isomer that we are looking for. Most supplements a…
What they were answering
Morgan76510 · 1 points
As far as electrolytes are concerned are you sure that eating well before is left 2 hours for digestion is not a more advisable solution in the sense that we are mainly HETEROTROPHES and we cannot photosynthesize from RAW minerals an amount will be assimilated by the body but this will be very minimal compared to the photosynthesis that a good meal can provide us with and furthermore the inorganic minerals will surely add a load to the kidneys during the trip, I mean if you're really looking to stay constantly fuelled by minerals you might as well take some vitamin supplements or the addition of vitamin B6 etc. will perhaps help the assimilation better ? What do you think about this have you studied this in naturopathy for example?
u/MisterYouAreSoDumb
The electrolytes are for the water intake, as MDMA can throw your electrolyte balance off and cause a bunch of issues. Plus, people can overheat on MDMA, so they tend to either drink not enough water, which is bad, or too much water, which is also bad. Taking electrolytes with your water allows you to keep that balance going much better than a meal beforehand would.