Comment · Tue, April 12, 2022
MDMA Supplementation
Original post in this thread
MisterYouAreSoDumb · 205 points
Ok, I did promise that I would make another post regarding supplementation to mitigate MDMA induced neurotoxicity. I have just been putting it off. Since my last post, I have gathered more information regarding my theory about MDA metabolism being the main cause of MDMA's neurotoxic effects. I will try to not get into that in this post, and keep this mostly about supplementation. As seems to be the norm with me, this may be long winded. Obviously everything I put on this list is not necessary. I will be placing supplements into different categories, with reasonings and references. I will let you decide which ones will be a part of your regimen.
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Essential Supplements:
* Alpha Lipoic Acid- This is one that everyone should be taking. It is a powerful antioxidant that scavenges reactive oxygen and nitrogen species. It also has a nice benefit of regenerating other vitamins, like C, after redox cycling. It exists in two enantiomers, R-ALA and S-ALA. R-ALA is the biologically active isomer that we are looking for. Most supplements a…
What they were answering
veilpasal · 2 points
Hey OP! Great and informative post and i appreciate you giving it out there for us. I just wanna ask if you only supplement as u are going to take mdma or you take supplements ahead of time (like taking all/some of the supplements everyday before the day of your roll). I have like a month for a festival so i just want to maximize the effects of all this. Would appreciate your answer thanks :)
u/MisterYouAreSoDumb
It's good to take the magnesium, CoQ10, and vitamin C every day leading up to it. Magnesium takes time to build up, and both CoQ10 and vitamin C are good daily.