Comment · Sun, January 30, 2022 · ND Owner
NMN formulation change
Original post in this thread
ROTHUM2 · 38 points
Has anyone else noticed a difference in efficacy between the old NMN tablets (sized like a small cylinder) versus the new one (sized like a small disc)?
I thought it was placebo at first, but with the old NMN, I noticed a profound increase in energy and well being. With the new NMN (disc shape), I notice nothing.
Thinking I may be tricking myself, I experimented on my wife. When I give her the old NMN, her energy noticeably improved. When I give her the new one, no difference.
I’m curious if anyone else has had this experience. I know /u/MisterYouAreSoDumb has mentioned the enteric coating on the new NMN is superior, but I can’t help but notice my consistent, personal experience.
UPDATE (Feb 2022)
They must have gone through several iterations, because the magic is back on my latest purchase. I’ve seen 3 different tablets — the cylinder (original), a larger flat circle with a powdery exterior, and the most recent, a smaller circle with a smoother exterior.
The only version that didn’t work for me was the one with the powdery exterior. The newest version works GREAT, perhaps even better than the original.
What they were answering
dsschmidt · 1 points
Oy vey! We live in an endless stream of lies and bullshit. Thanks.
What's your take on dosage equivalence, regular powder and enteric coated?
u/MisterYouAreSoDumb · ND Owner
That's tough to say without some direct pharmacokinetic lab comparisons. Subjectively for me, 125mg enteric feels like 400-500mg of straight powder. You can see one customer on this thread stated that the 125mg enteric tablets were too strong for him, so everyone is going to be different in their reactions. It would be hard to give a universal equivalence without some blood testing data over a larger sample size.