Comment · Thu, February 24, 2022 · ND Owner
⚠️ NEW PRODUCT RELEASES ARE COMING 3/03/22 | NMN 250mg Capsules, NMN Powder, Sabroxy 500mg Tablets, & Two New Mystery Products ⚠️
Original post in this thread
NDSocialMedia · 40 points
What they were answering
dirk23wright · 5 points
Why would you want a powder when you sell an enteric coated pill already? Isn't the powder going to be less effective? Are the capsules enteric coated as well?
u/MisterYouAreSoDumb · ND Owner
Yes, the powder will be less effective. However, some people have issues with the enteric coating, and others have too strong of effects and want to dose lower. We are giving people more choice. The enteric coated tablets are not going anywhere, and those will still be the most effective form. However, giving customers more options is always a good thing, as everyone is different. One size does not fit all.
The capsules are not enteric coated. We've done a lot of dissolution testing of capsules on the market claiming to be enteric, and they are all just lying. Every single capsule that has claimed to be enteric on the market has fully dissolved in 30-45min in simulated gastric fluid. They need to stay intact for 4 hours in gastric fluid, then dissolve quickly once they reach the neutral pH of the small intestine. Enteric capsules do exist, but the company that makes them won't sell to the supplement industry. They will only sell to you if you have a pharmaceutical manufacturing license. It's something to do with one of the ingredients used in the capsule shell. We'll keep working on possible solutions to enteric capsules, but they have to actually be enteric for us to use them.
Regarding stability, the synthesis route for NMN was changed. This has resulted in a more stable end product that does not need to be kept at low temperatures. There was something to do with the crystal structure of the NMN under the old synthesis that made it more susceptible to degradation. We've done a bunch of testing on the new batches, and they are stable at room temperature. This not only makes it easier from a production standpoint, but also makes it possible to sell in powder form.