Comment · Thu, November 22, 2012
How efficiently will my brain recover after amphetamine use?
Original post in this thread
Boobs_and_Hot_Cakes · 8 points
I recently saw a post on bluelight in regards to the regeneration of serotonin receptors following MDMA use, that same post claimed that dopamine production/receptors do not return to normal levels following methamphetamine abuse.
I use dextro-amphetamine at therapeutic doses on a regular basis, usually about 60-90mg a week. I was curious what level of damage this is doing and whether or not this damage is repairable.
Extra information
Exams are over so it's been about 10 days since my last dose, I'm not extensively addicted, I'm still able to do chores and accomplish tasks though slightly less efficiently and I do feel less inclined to socialize. I've been taking amphetamine for about 18 months and have a further 5 years left of university which I would consider using it for, at a decreased dosage of about 40-60mg a week.
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb
You need to be taking a highly bioavailable magnesium supplement every day. I take fully chelated magnesium glycinate. This will slow your tolerance to amphetamines as well as protect from excitotoxicity.
You also need to be taking antioxidants. Alpha lipoic acid needs to be one of them. I would also take grape seed extract, quercetin, and vitamins C and E. I would also add acetyl L-carnitine, as it has been shown to prevent toxicity from DA metabolites. It also goes very well with alpha lipoic acid.
You should also be taking Selegiline. It's an MAO-B inhibitor, and will protect you from dopamine's toxic metabolites by preventing them from being created. (Please note that you may need to adjust your dosing when combining selegiline and any dopaminergic drug, like amphetamine.)
Do that, and you will be good.