Comment · Tue, February 17, 2015 · Ceretropic
New at THT.co
Original post in this thread
kanooker · 41 points
Crebinostat
http://www.tht.co/cognitive-enhancement/Crebinostat
>Crebinostat is a potent small molecule inhibitor of histone deacetylases (HDACs).
HDAC inhibition upregulates the transcription factor CREB (cAMP response element-binding protein), which can improve memory and synaptic plasticity.
In a series of in vitro experiments, Crebinostat positively affected several transcriptional processes implicated in learning and memory, and aging-related cognitive decline. In an in vitro animal experiment, Crebinostat-treated mice demonstrated enhanced memory compared to untreated mice.
CNTF Peptide Fragment 147-150
http://www.tht.co/cognitive-enhancement/cntf
is a tetrapeptide that corresponds to amino acid residues 147-150 of the polypeptide hormone ciliary neurotrophic factor (CNTF). CNTF is neuroprotective and promotes neurogenesis in the hippocampus, but clinical use revealed unpleasant side-effects like substantial weight and muscle loss. The CNTF fragment 147-150 (DGGL) enhances hippocampal neurogenesis and neuronal plasticity, and improves cognition in mice, without the weight loss seen with CNTF administration.
F2MPA
What they were answering
hackallthethings · 1 points
Do you already have some of THT's GTS-21 incoming that you plan on testing? Just wanted to check since if you don't I can order some myself and send you the amount you need for the tests (specify). I guess I'm just really anxious to try this out. :D
Edit: I could also buy some and have it shipped to you directly if you ship me what remains after the tests, probably better that way since it would be faster and you'd get the product sealed.
u/MisterYouAreSoDumb · Ceretropic
I don't, but I can. I just have a lot on my plate at the moment. I can pay for the testing. I just don't have a ton of time to organize things.