Comment · Tue, February 10, 2015 · Ceretropic
New at THT.co
Original post in this thread
kanooker · 41 points
Crebinostat
http://www.tht.co/cognitive-enhancement/Crebinostat
>Crebinostat is a potent small molecule inhibitor of histone deacetylases (HDACs).
HDAC inhibition upregulates the transcription factor CREB (cAMP response element-binding protein), which can improve memory and synaptic plasticity.
In a series of in vitro experiments, Crebinostat positively affected several transcriptional processes implicated in learning and memory, and aging-related cognitive decline. In an in vitro animal experiment, Crebinostat-treated mice demonstrated enhanced memory compared to untreated mice.
CNTF Peptide Fragment 147-150
http://www.tht.co/cognitive-enhancement/cntf
is a tetrapeptide that corresponds to amino acid residues 147-150 of the polypeptide hormone ciliary neurotrophic factor (CNTF). CNTF is neuroprotective and promotes neurogenesis in the hippocampus, but clinical use revealed unpleasant side-effects like substantial weight and muscle loss. The CNTF fragment 147-150 (DGGL) enhances hippocampal neurogenesis and neuronal plasticity, and improves cognition in mice, without the weight loss seen with CNTF administration.
F2MPA
What they were answering
killword-noot · 1 points
FWIW, newstarnootropics' bromantane also has a distinctive smell. It smells very similar to Gak," the putty made by Nickelodeon. It's sort of a mix of earthy/soil and glue scents. I didn't notice Ladasten having any sort of smell when I crushed the tablets but I probably wouldn't have noticed.
u/MisterYouAreSoDumb · Ceretropic
Might be the same supplier. A couple people have PMed me now saying that they get good results from brand name Ladasten pills, but not from THT's powder. It's anecdotal, but fits my experience so far. There are also many people saying they react well to THT's Bromantane too.