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Comment · Sat, February 7, 2015 · Ceretropic

New at THT.co

Original post in this thread

kanooker · 41 points

Crebinostat

http://www.tht.co/cognitive-enhancement/Crebinostat

>Crebinostat is a potent small molecule inhibitor of histone deacetylases (HDACs).
HDAC inhibition upregulates the transcription factor CREB (cAMP response element-binding protein), which can improve memory and synaptic plasticity.
In a series of in vitro experiments, Crebinostat positively affected several transcriptional processes implicated in learning and memory, and aging-related cognitive decline. In an in vitro animal experiment, Crebinostat-treated mice demonstrated enhanced memory compared to untreated mice.

CNTF Peptide Fragment 147-150

http://www.tht.co/cognitive-enhancement/cntf

is a tetrapeptide that corresponds to amino acid residues 147-150 of the polypeptide hormone ciliary neurotrophic factor (CNTF). CNTF is neuroprotective and promotes neurogenesis in the hippocampus, but clinical use revealed unpleasant side-effects like substantial weight and muscle loss. The CNTF fragment 147-150 (DGGL) enhances hippocampal neurogenesis and neuronal plasticity, and improves cognition in mice, without the weight loss seen with CNTF administration.

F2MPA

http://www.tht.co/cognitive-enhancement/F2MPA…

What they were answering

redan-yadayada · 1 points

No. Never. I'd find that quite odd TBH.

u/MisterYouAreSoDumb · Ceretropic

I'm trying to isolate things now. My stomach has just gotten very upset every time I have taken it. Like muscle contraction cramping.

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