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Comment · Fri, May 14, 2021 · Natrium Health & Nootropics Depot

Inflamed Liver from Nootropics

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JJFlash120 · 261 points

I'm a 50 year old male, in decent shape, slightly elevated cholesterol but no other major health issues, rarely drink, no recreational drug use. I recently became interested in Nootropics to combat anxiety, stress, and fatigue. Being a Lawyer I need every edge I can get in the day to day. So I read the Nootropic Blogs, watched dozens of videos and read hundreds of pages on this Reddit Feed. Having done the research I started taking the following (all of which I bought at Nootropics Depot). My first week I started taking Lion's Mane then introduced each Noot 1 by 1 every couple of days, then finally taking the following Stack over 3 weeks:

Lions Mane 500 mg - 1x/dayCDP Citicholine 250 mg - 1x/dayL-Theanine 200mg - 1x/dayRhodolea Rosea 500mg - 1x/dayOxiracetam 750mg - 1x/dayNoopept 10mg (caused brain fog after 3 days / discontinued)Fish Oil (daily)L-Tyrosine 500mg (caused brain fog after 2 days / discontinued)

At around the 3 week mark, I developed pain and burning on my lower right side/flank which radiated into my back, and my belly and side became swollen. Found myself urinating every hour. Went to my Doc right away. He did blood work which showed increase liver enzymes. He the…

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u/MisterYouAreSoDumb · Natrium Health & Nootropics Depot

So there are two concepts that people are conflating with each other. One supplement REGULATION. The other is supplement ENFORCEMENT. This is why many people are confused about the situation. Dietary supplements are very regulated in the US. There are thousands of rules and regulations that supplement manufacturers have to follow. They mandate very specific things about every part of a supplement business. If companies do not follow those regulations, they can be fined and shut down. However, the issue then becomes with how often/well the FDA enforces those regulations. This is where people get the idea that the supplement industry is not regulated. It's not that there are not tons of rules and regulations that must be followed. It's that the FDA selectively enforces those regulations on only a small number of companies. This means that many brands can break the rules for longer than they should, because the FDA doesn't have the manpower to enforce it for everyone.

It's like speeding laws. If there are no police around to pull you over when you speed, it can seem like maybe the speed is unregulated. However, it's not. There is a speed limit, and if you break it you can get into big trouble. If you get caught going 120mph in a 60mph zone, you will be put in jail, fined, and maybe lose your license. Let's say there is only 1 police offer for a town of 200,000 people, though. If you are one of the people caught speeding, you can certainly have big problems. However, to the other 199,999 people it might seem like there are no speeding laws. It's just that the enforcement of those laws is not universal. Obviously that's an extreme example, and there are way more FDA agents than 1 per 200,000 companies. It gets the idea across, though. If the FDA is only selectively enforcing the regulations for a small number of companies, then you can have the potential for tons of bad actors in the industry to do bad things for a while. This is what you have in the supplement industry. It's not that it is unregulated. It's that it is sporadically enforced.

It's very similar to the SEC in the United States. That's the Securities and Exchange Commission. They regulate the stock market here. There are TONS of companies blatantly violating the rules with stock manipulation and other illegal shit on the stock market. However, the SEC only goes after very few of them. Also, when they do fine companies, it is for peanuts compared to what they made breaking the rules. That doesn't mean the stock market is unregulated. It's very regulated. It's just not properly enforced. You will find that with a lot of things in the US, in fact. It's not that we don't have regulations. It's that our federal agencies put in place to enforce them are shit. The dietary supplement industry is regulated just as much as many other industries in the US, like banking, stocks, air quality, etc. However, the issue is enforcement.

That's why a lot of people make the claim that dietary supplements are not regulated in the US. They very much are. It's just that federal enforcement is slow, sporadic, and not universal. What does happen a lot is civil lawsuits from lawyers using the FDA regulations to essentially privately enforce the regulations. You even get a lot of shady ones using it to essentially blackmail supplement companies. That's a whole other problem, which is made worse by how poorly a lot of the FDA regulations are written. They leave a lot of room for shady lawyers to interpret things in ways that cause tons of civil suits, and the FDA is slow and unwilling to correct those things most of the time.

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