Comment · Wed, December 4, 2019 · Natrium Health & Nootropics Depot
Dipeptide analogs of piracetam, noopept, sulpiride,... exhibiting far superior potency and specificity to their putative mechanisms.
What they were answering
Kjellisdebeste · 1 points
I guess I didn't quite get it. I'm still under the impression that they show optimized molecules. I've thought it to be clear for quite a while that the pyrrollidone group wasn't specific for anything.
I still don't understand the popularity of a substance that one has to ingest by the spoonful. It will have it's own specific profile, for sure.
u/MisterYouAreSoDumb · Natrium Health & Nootropics Depot
No, that's just the regular old noopept structure. They were just making the images that way to show how the structures were similar between noopept and piracetam. Noopept is proline and glycine with a phenylacetyl group to protect them. They were showing how proline and glycine can mimic the functional groups on piracetam. They were also talking about how they arrived at the noopept structure, and the intermediate peptides they investigated to get there. That might be where you are confused. They talk about a pyroglutamic acid-glycine peptide version, which is just the smallest peptide they could make with similar structures to piracetam. That led them to doing more improvement, which resulted in noopept.
Funny enough, I am not sure if anyone even realized we use pyroglutamic acid in our Alcohol Defense product. We didn't just do that by accident. We did that to help antagonize alcohol's effect at the NMDA receptor. We were inspired by the piracetam and noopept research to figure that out.