Comment · Tue, April 29, 2025 · ND Owner
Sleep Support combined with Tauromag and Magnesium Glycinate
Original post in this thread
shellvin1234 · 3 points
Hey guys,
I have taken Tauromag and Magnesium glycinate before bed and it has been decent for sleep so far. I was considering adding Sleep Support (because of neuroprotective effects) along with the Tauromag and Magnesium glycinate. Is this overkill?
What they were answering
ProperBeat · 3 points
That's how you get to the 10% levels like they claim.
They claim >1.2% and the related adenosine levels seem to be in line with that AFAIK. But what makes you believe they are using synthesised cordycepin and what would be the drawback of that? I've used it for quite some time now and the claimed effects are there, no doubt.
I read that cordycepin needs pentostatin to be present as well to have a therapeutic effect. Will you specify that?
u/MisterYouAreSoDumb · ND Owner
But what makes you believe they are using synthesised cordycepin
Statements from the suppliers in China that supply them. They also state that they mix in CS-4 Cordyceps mycelium in there. We have tested a bunch of CS-4. It doesn't have much, if any, cordycepin in it. This means that the cordycepin levels have to be from the fruiting body extract they have in there, but they don't state what the ratios are. They just say 900mg of the mixture.
what would be the drawback of that?
For cordycepin, not a ton. Cordycepin is cordycepin, whether or not use synthesize it in the lab. It's just not natively made, and the price of synthetic cordycepin makes the products expensive. Our goal is to make 1-2% cordycepin natively, without the need to extract or add synthetic sources. Then if you want to extract it, you can get much higher levels for the same price as existing extracts. Plus, this is all happening in Canada, not China. Some people value that. Not that we have anything against China. We have a lot of great partners there, and they do good work. It's just that many people want us to be more self-sufficient in North America. Also, there are other adenosine derivatives that have effects that you don't get if you make cordycepin synthetically. Part of our process is trying to figure out how to get the Cordyceps to make more of all the adenosine/uridine derivatives.
If someone were to say spike their lion's mane product with synthetic erinacine-A, it would be the same story. It would work like biosynthetically made erinacine-A, but be very expensive. Cordycepin has just been more fleshed out through synthetic processes. Making synthetic erinacine-A is still way too difficult and expensive for it to make sense, but I am sure one day that might not be the case. For now, our Erinamax has the most erinacine-A of any product on the market, and nobody is even close to us yet. There are many people trying to catch up, but they have not been able to get anywhere near yet. This is not a secret in the industry, either. Everyone out there testing erinacine-A in products now is using a reference standard made from our Erinamax. That's how Chromadex was able to get enough raw materials to make the standard. We have been working with Chromadex for years on standards. The erinacine-A one is made from our product. We also spoke to all the science people from around the industry at ICSB a couple weeks back. Everyone has been trying to catch up to our Erinamax, but it took us years and millions of dollars to do. We have a big head start. By the time people catch up, we will have the next generation ready, then the race starts again. People are starting to realize that, and in fact are going to start selling our Erinamax themselves.
We are likely pivoting to being more of an ingredient developer and supplier. That's where our passion is. We like to do science and R&D, then make the best products on the market. I hate the retail side of the industry. I would much rather just supply brands with ingredients, and focus on the lab and science side, than be a part of the scam retail side of this industry.
I read that cordycepin needs pentostatin to be present as well to have a therapeutic effect. Will you specify that?
The issue is that pentostatin is a drug in the US, so you can't even mention it on the label or in testing, or the FDA will come down on you. Cordyceps does make it biosynthetically, and it is implicated in the stability of cordycepin. However, because of its status as a drug, it makes it difficult to relay that information to consumers while staying compliant.