Comment · Sat, April 23, 2016
Which universities is Ceretropic partnering with and what research is being pursued?
Original post in this thread
narlsnarly · 4 points
Which universities is Ceretropic partnering with and what research is being pursued?
What they were answering
rmcfar11 · 1 points
I was referring to a previous comment, I recall, you had mentioned it having the right chirality? I may have mixed that up with something else. I'm surprised Pubchem gives it a 368 for complexity? It's a big molecule, but structurally simple.
Yeah, I just went and looked it up a little while ago. I already knew that it was a fatty acid and as such, it will just be a long carbon chain with a carboxyl group at the end. The only difference between the variations is the #C and un/saturated (Un in AA's case). It's a solid at STP right?
Anyways, assuming that they didn't make any errors in the outsourced batch (Ex. Prepped an intermediate of the peptide, and then it sat around for a while waiting for the AA to ship in, didn't add it in at a wrong step, like hydrogenation, or even carrying out the synth differently.) It would have to be something that occurred in transit. Maybe it picked up some humidity (I know it's a fat, so that's not really possible lol), or it could be as simple as a difference in using it right after it's been synthed, vs a batch that has been prepared so as to be viable for shipping, if you get what I mean?
u/MisterYouAreSoDumb
No, that was just me using the wrong term. I should have said conformation. The peptide lab we were working with seemed to think it could be made in different conformations, and that is why it was not working in the solid phase peptide synth. No idea if that is true or not. I have been meaning to circle back with them on it when I have some time.