Comment · Fri, June 13, 2025 · ND Owner
Anthocyanin-fucoidan nanocomplex
Original post in this thread
Warren_sl · 10 points
I thought this would be an interesting thing to share. Unsure if stacking Fucoidans and anthocyanins confer any similar benefit or not, but this could be an interesting product type to look into. Curious on its modulation of SIRT6 considering the affinity both Fucoidans and Anthocyanins have for it.
“Abstract
Anthocyanins, commonly extracted from aronia, exhibit excellent in antioxidant activity and anti-cancer activity. However, anthocyanins are not only easily oxidized in water but also rapidly disappear from the body, thus requiring a large amount of administration. To solve these limitations, we selected fucoidan, an anionic polymer, to produce an anthocyanin-fucoidan nanocomplex (AFNC) with enhanced absorption and chemical stability by ionic bonding and π-π stacking between anthocyanins. In vitro, AFNC showed increased cell permeability absorption and plasma chemical stability than free anthocyanins. AFNC suppressed the epithelial mesenchymal transition (EMT) signal including IκBα/NF-κB signaling pathway and the release of pro-inflammatory cytokines. In vivo, AFNC exhibited 3.24-fold higher bioavailability than free anthocyanin in rats. AFNC effectively suppressed the gene…
What they were answering
Warren_sl · 2 points
Not how I read it at all! I appreciated the information and context. Also awesome knowing the Alpha Glucan content in Erinamax, probably are alpha glucans that confer similar benefits to beta glucans depending on which you’re comparing.
I wonder if Vesta Nutra has any good methods for looking at beta glucans, they have a product called BetaImmuneShield that claims to basically just be Beta-1,3 D-Glucan from Algae.
u/MisterYouAreSoDumb · ND Owner
Well look at this one.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9961350/
Alpha-glucan from black beans that fights cancer.