Comment · Mon, June 16, 2025 · ND Owner
Anthocyanin-fucoidan nanocomplex
Original post in this thread
Warren_sl · 10 points
I thought this would be an interesting thing to share. Unsure if stacking Fucoidans and anthocyanins confer any similar benefit or not, but this could be an interesting product type to look into. Curious on its modulation of SIRT6 considering the affinity both Fucoidans and Anthocyanins have for it.
“Abstract
Anthocyanins, commonly extracted from aronia, exhibit excellent in antioxidant activity and anti-cancer activity. However, anthocyanins are not only easily oxidized in water but also rapidly disappear from the body, thus requiring a large amount of administration. To solve these limitations, we selected fucoidan, an anionic polymer, to produce an anthocyanin-fucoidan nanocomplex (AFNC) with enhanced absorption and chemical stability by ionic bonding and π-π stacking between anthocyanins. In vitro, AFNC showed increased cell permeability absorption and plasma chemical stability than free anthocyanins. AFNC suppressed the epithelial mesenchymal transition (EMT) signal including IκBα/NF-κB signaling pathway and the release of pro-inflammatory cytokines. In vivo, AFNC exhibited 3.24-fold higher bioavailability than free anthocyanin in rats. AFNC effectively suppressed the gene…
What they were answering
tyham · 1 points
turkey tail is seen as a drug by Google
Any idea why? Was some pharm company developing it?
Or was someone just boofing turkey tail.
u/MisterYouAreSoDumb · ND Owner
Yeah, because PSK and PSP from Turkey Tail mushroom are approved drugs in Japan, and drugs.com has them listed idiotically.
https://www.drugs.com/npp/turkey-tail.html
T. versicolor extract (ie, PSK) is approved as a pharmaceutical-grade medicine in Japan and has been used for more than 30 years as a treatment for cancer.
The product approved as a drug in Japan is a very specific extract of liquid culture mycelium made by a single company. However, these stupid sites talk about it as if Trametes versicolor itself is a drug. This makes Google flag us as selling drugs. It's retarded.