Comment · Fri, April 26, 2013
MDMA: The 'Dont Re-dose' advice?
Original post in this thread
KosherDev · 25 points
So this came up in another thread and people suggested I make my way over here for a more specific answer.
We've all heard the general advice of not re-dosing on mdma to minimize any potential harmful after effects. It makes sense but is it the act of just 'taking more' that could cause issues, or is it the actual time separation?
So the example. You take an initial 120mg dose, and then a subsequent 60mg dose an hour or so later for a grand total of 180mg.
Vs.
One initial dose of 180mg.
Are they equally 'bad' or does the subsequent dosage cause more complications than one large initial dose? If so, why?
What they were answering
Dr_Uncle · 1 points
After I read this http://www.erowid.org/chemicals/mdma/mdma_neurotoxicity1.shtml
I decided that optimal dose for effects without high risk of single-dose neurotoxicity is D< 1.25mg/kg body mass. Any comments on this?
u/MisterYouAreSoDumb
Generally that is a good dose. It all depends on many factors like body temperature, diet, genetics. With supplementation you can go higher than that without issue.