Comment · Thu, April 25, 2013
MDMA: The 'Dont Re-dose' advice?
Original post in this thread
KosherDev · 25 points
So this came up in another thread and people suggested I make my way over here for a more specific answer.
We've all heard the general advice of not re-dosing on mdma to minimize any potential harmful after effects. It makes sense but is it the act of just 'taking more' that could cause issues, or is it the actual time separation?
So the example. You take an initial 120mg dose, and then a subsequent 60mg dose an hour or so later for a grand total of 180mg.
Vs.
One initial dose of 180mg.
Are they equally 'bad' or does the subsequent dosage cause more complications than one large initial dose? If so, why?
What they were answering
DownWithLucy · 1 points
I'm assuming you use Vitamin C to acidify the urine in the same way people do with amphetamine. The antioxidative properties of the VitC are helpful aswell.
What would a suitable CYP3A4 inhibitor be?
u/MisterYouAreSoDumb
Exactly. Vitamin C also protects from hepatotoxicity, so it's a win/win
I use grapefruit juice to inhibit CYP3A4. Piperine seems to work well too.