Comment · Tue, April 30, 2013
MDMA: The 'Dont Re-dose' advice?
Original post in this thread
KosherDev · 25 points
So this came up in another thread and people suggested I make my way over here for a more specific answer.
We've all heard the general advice of not re-dosing on mdma to minimize any potential harmful after effects. It makes sense but is it the act of just 'taking more' that could cause issues, or is it the actual time separation?
So the example. You take an initial 120mg dose, and then a subsequent 60mg dose an hour or so later for a grand total of 180mg.
Vs.
One initial dose of 180mg.
Are they equally 'bad' or does the subsequent dosage cause more complications than one large initial dose? If so, why?
What they were answering
Narit · 1 points
Is that legal to order in the US or has it been scheduled? My problem is I already have quite a good amount of MDA that I was planning on using.
How sure are you of the 6-APB not having the neurotoxicity? Hasn't less researched been performed on this substance since it is relatively new?
u/MisterYouAreSoDumb
It's legal, as long as it's not for human consumption. I'm very certain it's not neurotoxic to 5-HT neurons like MDA is. However, it's harder on your heart, due to the vasoconstriction.
You can take the MDA, but you'll need a lot of antioxidants to make it safe. ALA, ALCAR, vitamin E, NAC. It will be harder to fully protect, but it's possible. If you can completely inhibit your CYP2D6, then you can really stop the toxic metabolites. However, I have not tried.