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198 matches · Milk thistle

Commentr/NootropicsDepotJun 9, 2026

Eurycomax - my (almost 1 year update)

Replying to lewanay · That would be amazing! And there is a huge market for supplements around the peripartum period. Even starting with galactagogues (Moringa, Torbangun, Fenugreek, Milk Thistle and se

Yep, that's the one we used; specifically HiPP from the Netherlands. They leave the starch out of that one that the German one has, but they have both pre and probiotics in it that the UK one doesn't.

2Tongkat aliMilk thistle
Commentr/NootropicsDepotFeb 18, 2026

Behind the Scenes at Nootropics Depot: Inside Our Pharmaceutical-Grade Testing Labs 🧪

Replying to MrRADicalKMS · That is marvelous news! On a side note that is a little more unrelated, will you guys ever sell any of the more common herbs that are often used in teas, and some of the little mor

Yes, we have worked on both chamomile, valerian, and garlic. In fact, we had a chamomile that felt like a benzo! It was crazy. It was only stable in an ethanol tincture, though, so we never brought it out. I can revisit it, though. It was a really cool one. The same goes for vale…

8Milk thistle
Commentr/NootropicsDepotDec 22, 2025

Alcohol Question - Supplements to Prevent the Damage?

Replying to mbvlover25 · NAC, Milk Thistle & Tudca

The same goes for NAC. You have to take NAC before drinking alcohol, or it makes the damage worse. It's because of a dual stage pharmacokinetic profile that results in toxic metabolites being made by NAC if alcohol is already in your system, where that metabolic pathway is avoide…

13Milk thistle
Commentr/NootropicsDepotDec 22, 2025

Alcohol Question - Supplements to Prevent the Damage?

Replying to mbvlover25 · NAC, Milk Thistle & Tudca

You have to be really careful with TUDCA and alcohol. Let me break this down, as there's a lot of confusion around TUDCA and alcohol timing. Many companies say that you should avoid TUDCA within 24 hours of consuming alcohol. However, the whole "24-hour rule" thing isn't as black…

16DosingMilk thistle
Commentr/NootropicsDepotNov 28, 2025

Our Black Friday Sale 2025 is officially live!

Replying to AAAUUUUAUAUAUUAUA · Very exciting, just dont release too much cool stuff, i need to stay around 300 dollars in total and ill probably need to stock up on some essentials by then... Ive seen some of t

No, new designs will not raise prices. Bottle cost will go up, but our label cost might actually go down. Printing in house costs a lot, with the cost of stock, ink/toner, and maintenance of our printers. Having a professional printing company do them for us can actually make it…

4Lion’s maneApigeninFisetinQuercetin
Commentr/NootropicsDepotOct 18, 2025

Anyone know why so many supplement companies can't reach Prop 65? It's a California strict policy limit on heavy metals (an other things like water purity).

Replying to anexanhume · I personally use ND, Now, Nutricost, Sports Research, and Life Extension in my stack. They all have good reputations for meeting label claim and being relatively cost effective. I

Not sure if you have seen some of my recent comments on Nutricost, but I'll share them here as well. [Take a look at the results of some saffron testing we recently did.](https://cdn11.bigcommerce.com/s-cebedmpn/images/stencil/original/content/img/pdp-value-prop/Saffron-Market-Da…

8COASaffronMilk thistle
Commentr/NootropicsDepotJul 30, 2025

⚠️ NEW PRODUCT RELEASES ARE COMING 07/31/25 | Three Mystery Products, Mushroom Magic Magic Powder Blend, Mushroom Magic Advanced Powder Blend & TUDCA⚠️

Replying to Warm_Ad_6177 · There was an in vitro study with human liver cells that concluded that pre-treatment with TUDCA markedly increased cell damage by alcohol, though there were benefits through a diff

I actually wrote a pretty good overview of the issue with TUDCA and alcohol. https://reddit.com/r/NootropicsDepot/comments/1ipimsj/milk_thistle_is_beneficial_to_the_liver_fact_or/mcyj7jp/

5COADosingMilk thistle
Commentr/NootropicsDepotApr 5, 2025

NOW Foods supplements - not quality tested?

That's a total lie. NOW has their own lab, and their lab director knows what she is doing. Their products are never going to have 0% of the actives. That's a silly stupid thing to say. We have tested some of their stuff that has come in below label claim, but never something that…

12Milk thistle
Commentr/NootropicsDepotFeb 15, 2025

Milk Thistle is beneficial to the liver! fact or fiction?

Replying to CaptainExcellent5299 · I've never found exact science on it. [https://help.bodybio.com/en-US/tudca-and-alcohol-355853](https://help.bodybio.com/en-US/tudca-and-alcohol-355853) Here Nutricost says best

Hey! Let me break this down, as there's a lot of confusion around TUDCA and alcohol timing. The whole "24-hour rule" thing isn't as black and white as some companies make it seem. Here's what's actually happening in your body: TUDCA and alcohol basically fight for the same metabo…

4DosingMilk thistle
Commentr/NootropicsDepotFeb 14, 2025

Milk Thistle is beneficial to the liver! fact or fiction?

Replying to Suspicious_Effort161 · Thank you for a in depth response I was hoping you would answer. I’ve often wondered if many studies have shown somewhat negligible effects is due to a lack of a standardized ext

That and study design. Milk thistle, through its silymarin content, has multiple mechanism for protecting the liver: * Antioxidant properties, scavenging free radicals and reducing oxidative stress * Anti-inflammatory effects, modulating enzymes associated with cellular damage, f…

7Milk thistle
Commentr/NootropicsDepotFeb 14, 2025

Milk Thistle is beneficial to the liver! fact or fiction?

Replying to isaarg · People say they can tell the cheap tudcas are good from the taste, but only let's you know it is a bile acid, not true tudca or udca. To make tudca or udca it takes multiple extra

I highly doubt anyone can really tell the quality of TUDCA by taste, unless they have calibrated their taste buds using properly assayed batches, and those impurities have specific flavors. Assay against a validated reference standard is the only real way to tell purity. Our sens…

7Milk thistle
Commentr/NootropicsDepotFeb 14, 2025

Milk Thistle is beneficial to the liver! fact or fiction?

Replying to isaarg · Best thing for liver unless you have a fully biliary obstruction is quality TUDCA or UDCA, it is available as a supp but is also fully studied and proven medication for a variety o

We are working on TUDCA as we speak. It was always a pricing issue. We could never make the pricing work with what other brands were charging, and what it actually cost us for high quality TUDCA. We assumed everyone was using lower quality sources, but people wouldn't pay 2-3X mo…

26Milk thistle
Commentr/NootropicsDepotFeb 14, 2025

Milk Thistle is beneficial to the liver! fact or fiction?

Yes, it is effective. However, it has to be a standardized silymarin extract. Just regular milk thistle is not effective. You have to have a highly standardized silymarin product. Also, milk thistle has another compound in it called silychristin. This compound inhibits the thyroi…

18Milk thistle
Commentr/NootropicsJun 15, 2024

ConsumerLab vs. Nootropics Depot

Replying to verifitting · > They say that Swanson was using UV-VIS, and outdated an inaccurate methodology, so that excuses them lying to customers and giving less than stated Wait, what..?

Yep! It's even worse... Consumer Lab made Swanson their TOP PICK, even though it failed their testing! So not only did they overlook not meeting label claims, and try to explain away not having what customers are being told it has by pointing to methodology issues, they tell cust…

3Milk thistle
Commentr/NootropicsJun 13, 2024

ConsumerLab vs. Nootropics Depot

Replying to tyham · > Swanson claimed to have 205mg silymarin. Consumer Lab only found 137.5mg, just 67% of what they claimed. However, CL PASSED THEM ANYWAY!!!! They say that Swanson was using UV-VIS

Really makes you wonder, right? We don't pay Consumer Lab. Swanson does. They treat us differently... What does that sound like?

5Milk thistle
Commentr/NootropicsJun 13, 2024

ConsumerLab vs. Nootropics Depot

Replying to AM_OR_FA_TI · You seem upset. Here are some Swanson test results and awards, now you share yours. 🤗 These are some of the ConsumerLab.com distinctions awarded to Swanson products: • ⁠Swanson

I test Swanson stuff all the time. I know what is (and isn't) in their products. You said these results validated your support of Swanson, when Swanson failed and had the least of any brand tested. I was correcting the record on the data. If you want to reject reality to insert y…

8Lion’s maneAshwagandhaCOAMilk thistle
Commentr/NootropicsDepotJun 3, 2024

Doubts about EGCG

I take our EGCG tablets every day. I take reduced glutathione with it to support the liver, and some days take our low silychristin milk thistle 1) Empty stomach 2) Very very rare, but you can take other supplements to support the liver with it. 3) Yes, it combines very well if y…

5QuercetinMilk thistle
Commentr/NootropicsDepotApr 26, 2024

Tongkat Ali Tablets and Low Silychristin Milk Thistle

Replying to verifitting · > Plus, they are being weird with Tongkat for some reason First Paypal and now Amazon, too??

Amazon is always weird.

1Tongkat aliMilk thistle
Commentr/NootropicsDepotApr 26, 2024

Tongkat Ali Tablets and Low Silychristin Milk Thistle

Replying to [deleted] · /u/MisterYouAreSoDumb Is there any chance you can direct me towards the bitterness receptor research?

https://www.sciencedirect.com/science/article/pii/S1882761608000549 https://www.sciencedirect.com/science/article/pii/S0006295222000090 https://www.sciencedirect.com/science/article/abs/pii/S0950329317300885 https://www.sciencedirect.com/science/article/abs/pii/S0022103116304899

2Tongkat aliMilk thistle
Commentr/NootropicsDepotApr 17, 2024

Tongkat Ali Tablets and Low Silychristin Milk Thistle

Replying to Sea-Animal8671 · How does one procure tablet form of TA from amazon?

Amazon is being stupid right now. They just upped the costs to get things into their warehouse 500% over night. That's not a typo. FIVE HUNDRED PERCENT! Brands are pissed right now because of it. It's totally fucked our margins on there. Plus, they are being weird with Tongkat fo…

2Tongkat aliMilk thistle
Commentr/NootropicsDepotApr 12, 2024

Tongkat Ali Tablets and Low Silychristin Milk Thistle

Replying to Phonafied · I have been preparing my taste buds for months with pure TA 10% powder on my tongue just so I can suck on these tablets like sour jolly ranchers, repeatedly banging my head on my c

When I die, I will be buried with a bunch of ND shit all around me like the pharaohs were. I'll have urns of Tongkat extracts placed next to my sarcophagus.

11Tongkat aliMilk thistle
Commentr/NootropicsDepotApr 12, 2024

Tongkat Ali Tablets and Low Silychristin Milk Thistle

Replying to inverted333 · What we really need is Tongkat suppositories.

Anything is a suppository if you try hard enough!

4Tongkat aliMilk thistle
Postr/NootropicsDepotApr 10, 2024

Tongkat Ali Tablets and Low Silychristin Milk Thistle

Hey everyone. I just wanted to let you know that we have Tongkat Ali 10% tablets back up. As many of you know, we initially launched the 10% Tongkat in tablet form. However, many people complained about the strong taste, so we moved to capsules instead. As I probably should have…

7516Tongkat aliMilk thistle
Commentr/NootropicsDepotMar 12, 2024

Why not capules all the time

Replying to spread_nutella_on_me · >We originally had them as tablets, but people complained about the taste, so we moved to capsules. Then people complained they liked the tablets better, so we can't win! LOL. Th

You'd be surprised. I don't think people realize just how many stupid things we deal with in a month. Some people chew the tablets and then complain. Some people take powders like berberine or milk thistle and put them into smoothies, then complain it tastes like ass. Some people…

3Milk thistle
Commentr/NootropicsDepotMar 8, 2024

Prices for regular international shipping have doubled?

Replying to chris106 · Thanks for the reply! I will contact your service team regarding the matter. If this is just some technical hick-up, all the better. I'll report back. Certainly wasn't my intenti

Figured it out! We have a new inventory control person, and he accidentally switched the milk thistle to 1.2lbs instead of 1.2oz... It has been fixed, and we will use it as a training opportunity for him. Thanks for alerting us!

5Milk thistle
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