Archive

InfiniEYE?

Replying to lewanay · I tried it and it didn’t budge my LDL at all. I also learnt that in the US, FDA doesn’t allow red yeast products to contain significant amounts of monacolin K, that actual compound…

Interesting to hear you say that, because our marketing manager found the same thing. He had high cholesterol, took the Thorne Choleast 900, and his cholesterol did not go down. So perhaps they are not one I should put any trust in. >I also learnt that in the US, FDA doesn’t allo…

Longvida consistently potentiates cannabis???

Replying to AAAUUUUAUAUAUUAUA · Ohh good, thank god you lack self control! Yeah thats super cool honestly, and i think its good to highlight a lot of the stuff that you seem to have been doing for a while aswell,…

> Another website? Did you guys not update it like a year ago or less? Not a new ND website. This is a full website for the Future Nutra Foundation, the nonprofit we are working on. >As much as i appreciate all the time you put into this, i do hope you have time to spend with you…

Rephyll Piperine content?

It has zero piperine. It's an extract that only pulls over the β-caryophyllene and then microencapsulates it. The other 94% is that patented microencapsulation system. Terpenes like β-caryophyllene exist as oils. They are volatile oils, which is why you don't see more products us…

Longvida consistently potentiates cannabis???

Replying to Ashamed-Status-9668 · Thank you. This is our current stack we have both taken for a bit over a year now other than the eggshell membrane. The stack is really dialed in for us as it has my wife's insomni…

I'll have to look into eggshell membrane a bit more to understand the mechanisms. I will say that addressing the bone mineralization thing in aging women early is a good idea. It's a hell of a lot easier to slow down the process than to reverse it once it is far along. All women…

Longvida consistently potentiates cannabis???

Replying to Ashamed-Status-9668 · Once a year we do. She goes in November. I think so as well. Getting her to do HRT is another topic.

I would suggest doing something like Function Health, where you get a larger panel once a year, and then a mid panel at the 6 month mark. You can also order more tests in between as well. Once a year is likely the bare minimum at your ages. Having more regular testing is crucial…

Longvida consistently potentiates cannabis???

Replying to Ashamed-Status-9668 · Exactly. It's why when my wife started having knee pain overnight we trialed every curcumin you sell and I made note of how often she woke me up at night, lol. I'm certainly not as…

Sounds like estrogen. Are you guys doing regular comprehensive blood panels? That will tell you for certain if it is estrogen or more systemic inflammation.

Longvida consistently potentiates cannabis???

Replying to AAAUUUUAUAUAUUAUA · Yeah its super wierd and interesting, i saw that some people reported feeling "thorny"/ irritable on it, when i first strated looking into it i saw that there was a study that said…

Ohh, I am not saying I won't still drop shit here and there on Reddit. I pretty much can't help myself, so I likely will still be doing that. LOL. However, I want to also professionally memorialize our efforts in a formal way. This means publishing full papers in respected journa…

Longvida consistently potentiates cannabis???

Replying to AAAUUUUAUAUAUUAUA · That could be why, but the pharmacokinetic studies do seem to suggest that its not the entire story. The best affinity of curcumin and its metabolites that i found was about 700 nm…

Yes, for sure it is not the only story. It's always more complex than it is initially thought. Your assessment of Longvida's ability to get curcumin and its metabolites to the brain in meaningful enough concentrations to affect MAOI is certainly warranted. However, I still think…

Longvida consistently potentiates cannabis???

Replying to Ashamed-Status-9668 · I was taking it at dinner so it took a while to really impact me. It got increasing worse to the point a cup of coffee in the morning would be so stimulating my hair would feel lik…

Yeah, and Meriva not doing it really shows the difference in pharmacokinetics. It seems to stay more peripheral, where Longvida does seem to reach the brain quickly. It's a good example for why simplifying things into just "more bioavailability equals more effects" isn't a good i…

Longvida consistently potentiates cannabis???

Replying to Ashamed-Status-9668 · It did that with caffeine for me too. Meriva didn't though.

That's because of the MAOI effects. I actually can't take Longvida with caffeine if I am on my larger AMPK stack, as I get overstimulated.

Longvida consistently potentiates cannabis???

Yes, by its MAOI activities. It can also help reduce the memory side effects of cannabis, by inhibiting COX-2. [Δ9-THC-caused synaptic and memory impairments are mediated through COX-2 signaling](http://www.cell.com/article/S0092867413013603/pdf) [Regulation of COX and LOX by cur…

Ok Amazon vs ND site saffron edition for

Replying to meatspin6969 · I have noticed the new ND Google ads and think they're pretty good! I'm glad you're finally putting more resources into marketing because no offense, you guys really need it. I h…

>1. Mind turning around the 4th bottle in the sixth pic and taking a picture of the ingredient list? You will see tomorrow! >2. Marketing is a brutal and many times dishonest industry. I think it's admirable that you're trying to stay in the loop and going down into the trenches,…

Is there a deadline for sulforaphane product release?

Replying to blueapple2025 · What made you go for sulforaphane in the end as a product , is their something specific and unique about it? I always thought nrf2 was the interesting thing about sulphoraphane bu…

It's the most studied. However, we are also working on a bunch more isothiocyanates in addition to sulforaphane. We have a comprehensive isothiocyanate stack from a bunch of different species in development at the same time, and are developing and validating a total isothiocyanat…

⚠️ NEW PRODUCT ALERT | Ecklonia cava Capsules⚠️

Replying to PeterLoew88 · What are some popular supps you’d recommend avoiding with tongkat in this regard? I have your tongkat 10% but haven’t tried it yet. I was considering taking it with Shilajit, boro…

Horny Goat Weed, Panax ginseng leaf, beta ecdysterone, boron

NOW Foods supplements - not quality tested?

Replying to Aldarund · 100micron? Do you mean 100nm? Also isn't liposomes could be way large eg. Multivesicular vesicles: >1000 nm. https://www.creative-biolabs.com/lipid-based-delivery/classification-…

Correct, nm, not micron. I mistyped. Also, 1,000nm particles are not really liposomes. They are called multivesicular bodies (MVBs). They lack the structural and functional characteristics necessary for effective compound delivery, primarily due to poor permeability, rapid cleara…

petition for ND to change the filler 'maltodextrin' to something else

We almost never use maltodextrin in our formulations. We purposely avoid it, not because of compelling science, but because it is just easier to agree and move on than fight that fight. However, what most consumers don't realize is that maltodextrin is the most common spray dryin…

Nootropics depot shilajit tested by ConsumerLabs

Replying to Ashamed-Status-9668 · I noticed a similar dosing game just recently with Pure Encapsulations CurcumaSorb aka Merica Curcumin Phytosome. They used 250mg capsules, so you have to take 2 of them for the 50…

We always set our dosing and capsules based on how the product is used, not what is best to trick consumers. It's a shame that so many people don't see the value in what we do. Consistent pricing and consistent dosing based on product usage should be the norm, not the exception.…

The New Nootropics Depot Is Now Live!

Replying to Ashamed-Status-9668 · It looks great and man the pages load really fast. I place and order and it was snappy. I wish you accepted Discover for payment as I like my cash back, but I digress. When I go …

Discover got weird a few years back, and started blacklisting supplement companies. Brands were losing their processing accounts because of it, so we had to remove Discover. I can check to see if the situation has changed recently, though. We are still working through a bunch of…

⚠️ NEW PRODUCTS ALERT | InfiniLYTE Powder & Berbelean Capsules ⚠️

Replying to ShockLatter2787 · Def interested in the Calebin-A extract, both how it feels in isolation, and why you landed on it in particular for this stack. You go into it slightly on the product page but I'm …

Sabinsa has been really trying to get us to bring it out for a while. They spent years developing it. It was a really cool story! They were doing a bunch of research on turmeric, and how to improve its bioavailability and effects. When they were doing some lab testing, they found…

Emptied a C3G capsule into my drink blend and voila, blood, blood, bright red blood. Or really I guess a deep pomeranate-esqe wine color that you would expect.

Replying to MDL999 · Its a cool Idea but Im not sure you wanna do that, i think that will stain your teeth.

It's definitely strong colored, but it is not hydrophobic, so it will wash off. So the color will be temporary. Something like curcumin will certainly stain your teeth, because it is hydrophobic.

MYSAD's Stack June 2024

Replying to wavyeggs · Can you elaborate on what overstimulation from AMPK feels like to you? I feel that I may run into this from time to time when I start adding a few things in (rhodiola, Hesperidin, …

I am just much more on edge and quicker to snap at things. It's not a lethargic feeling for me. It's an edgy over-stimulation. It's usually a combo of the AMPK effects and MAOI effects. I have found with a lot of trial and error that I can only take curcumin if the rest of my sta…

MYSAD's Stack June 2024

Replying to sonnsonn · No creatine ??? What a chump lol jk but seriously idk why he wouldn’t take it

I'm not currently working out, so I am not taking creatine at the moment. I am also taking a lot of things that hit AMPK, which means curcumin over-stimulates me if I add it in.

MYSAD's Stack June 2024

Replying to Ashamed-Status-9668 · Yeah, why I wasn't trying to argue that point. I was just clarifying what u/fakerzzz was getting at. I'm at 8 supplements a day and it seems like a lot to me(I have about 20 years…

[Rookie numbers!](https://media2.giphy.com/media/v1.Y2lkPTc5MGI3NjExZTcyd2RxYXMzOTMwYXFjMTk4b2k0bGxqMWJqaDV2bzN6NXJqYmI4cyZlcD12MV9pbnRlcm5hbF9naWZfYnlfaWQmY3Q9Zw/624P6yxUw2HwT9Sxs6/giphy.webp)

Pomegranate seed oil request, high in non-feminizing 17-Alpha-Estradiol which boosts lifespan in male mice

Replying to whereismyface_ig · I get that you have to make products that people buy, but then you introduce products that are variations of something and ppl get confused on whether they should purchase the new …

I totally understand your perspective. Part of that stems from our poor website layout and marketing. It's confusing for people because we really don't hand hold anyone. We give people access to a lot of different things, but we force them to figure out what works best for them.…

Pomegranate seed oil request, high in non-feminizing 17-Alpha-Estradiol which boosts lifespan in male mice

Replying to whereismyface_ig · imagine ND actually looking into product requests instead of working on their 20th variation of cistanche / red reishi / berberine / boswellia / rhodiola / curcumin / NAD / etc

You want another glutathione? I'm sure I could find another functional group to acetylate. Just say the word, buster! How about another ashwagandha? Maybe a pre-digested acid hydrolyed glycowithanolide extract? It'll blow your dick off! I'll release ashwagandhas till the end of y…