Comment · Mon, October 6, 2025 · ND Owner
Longvida consistently potentiates cannabis???
Original post in this thread
ThisIsCreativeAF · 21 points
So I've been occasionally taking Longvida and every time I take it, it seems to potentiate smoked cannabis quite significantly (even 8+ hours after taking Longvida). I'm curious if anyone else has experienced this? I've heard of people using turmeric/curcumin to potentiate things before, but wasn't expecting it to work this well. I actually don't take it very much because it can potentiate it to an uncomfortable extent for me as I'm fairly prone to get some anxiety from THC.
What they were answering
Ashamed-Status-9668 · 4 points
I was taking it at dinner so it took a while to really impact me. It got increasing worse to the point a cup of coffee in the morning would be so stimulating my hair would feel like it was growing. It's nice that Meriva doesn't do that and the wife and I both get the inflammation reduction we were seeking. In fact Meriva seems to be a bit longer lasting as my wife doesn't have knee pain at night ever since we started Meriva a little over a year ago.
u/MisterYouAreSoDumb · ND Owner
Yeah, and Meriva not doing it really shows the difference in pharmacokinetics. It seems to stay more peripheral, where Longvida does seem to reach the brain quickly. It's a good example for why simplifying things into just "more bioavailability equals more effects" isn't a good idea. Just getting more to absorb into the body isn't the same as getting it to all the places it needs to go in the body. Pharmacokinetics is just as complex as the pharmacodynamics of the product itself.