Dopamine synthesis without using a dopamine releasing agent?

Comment · Tue, July 21, 2020 · 1 pts

Come again? Not sure I understand what you are asking.

Comment · Wed, July 22, 2020 · 1 pts

Ohh, I had to click on the link above you. Got it. Was totally confused in my inbox! LOL Yes, agmatine also protects against β-amyloid, but not because of NMDA. https://sci-hub.tw/10.1007/s11033-018-4501-4

Comment · Wed, July 22, 2020 · 2 pts

I don't see any reason you should be worried about the combo, no.

Comment · Wed, July 22, 2020 · 2 pts

I'm happy to help! I love learning, and I love it when other people are interested as well!

Comment · Wed, July 22, 2020 · 1 pts

For up-regulation of dopamine, you are know the common ones. Uridine, Inositol, ALCAR, Sulbutiamine, and Forskolin are the main ones. Cordyceps up-regulates D2 receptors, too. Not sure I have any better alternatives. Exe

Comment · Wed, July 22, 2020 · 2 pts

Other than L-tyrosine or L-DOPA, not really. You could just try up-regulating tyrosine hydroxylase. It looks like low dose aspirin does that. I will have to research it a bit more. https://link.springer.com/article/10.1

Comment · Thu, July 23, 2020 · 3 pts

Tyrosine hydroxylase is the enzyme that converts tyrosine to L-DOPA. Then L-DOPA gets converted to dopamine by aromatic L-amino acid decarboxylase. So those two enzymes are responsible for how quickly you produce dopamin

Comment · Fri, July 24, 2020 · 2 pts

Dopamine beta-hydroxylase is a different enzyme. That's the one that controls the conversion of dopamine to norepinephrine. [See here](https://upload.wikimedia.org/wikipedia/commons/thumb/a/a3/Dopamine_beta-monooxygena

Comment · Fri, July 24, 2020 · 2 pts

We can look into California poppy. It was not really on our list, but I can add it. We have not yet settled on a standardization or extraction method that we want for skullcap. So we are still in the R&D phase.