Comment · Thu, December 8, 2016 · Ceretropic & Nootropics Depot
What they were answering
Plasticperson32 · -2 points
P21 is safe to take. Cerebrolysin uses Cyptic peptides. P21 is a segment of the THE peptide of focus.
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
I would not purport it as safe, since we don't have human studies behind it. I see no evidence to say it is unsafe, but that's not the same thing as safe. I tagged it as high risk because of how new it is.
Comment · Wed, December 7, 2016 · 11 pts
Roger that. I'll put it on the list.
Comment · Thu, December 8, 2016 · 16 pts
Wrong P21. That's a completely different compound. This is the P21 we are selling: http://imgur.com/a/mwkTy It's a an N-acetylated peptide with the amino sequence DGGL, which is aspartate-glycine-glycine-leucine, with
Comment · Thu, December 8, 2016 · 5 pts
That's the wrong P21 srubek!
Comment · Thu, December 8, 2016 · 5 pts
Negative, no human studies. We are the only ones to ever really synthesize it in any real quantities. N-PEPT-12 is just an attempt to make an orally bioavailable version of the peptides from Cerebrolysin, but I do not s
Comment · Thu, December 8, 2016 · 8 pts
Haha, that defeats the purpose of trying to avoid confirmation bias altogether.
Comment · Thu, December 8, 2016 · 11 pts
I saw that. It's fixed now. My web guy thought he was being helpful, not knowing it was a completely different P21. There is no Wikipedia entry for this P21.
Comment · Thu, December 8, 2016 · 3 pts
Yeah, that's fixed now. My web guy did not know this P21 did not have a Wikipedia entry.
Comment · Thu, December 8, 2016 · 5 pts
My histamine issues occasionally happen with both nasal and sub-Q. I have not tried it IM, though.
Comment · Thu, December 8, 2016 · 4 pts
Studies usually use 50-100mcg nasally (1mcg/kg).
Comment · Thu, December 8, 2016 · 4 pts
Studies have shown that nasal ROA is over 10X as effective as IV. So nasal seems to be the most effective ROA. 1mcg/kg was used in the study for nasal.
Comment · Thu, December 8, 2016 · 8 pts
I'll definitely look into it. It seems interesting. I'll have to see how economically feasible it is.
Comment · Thu, December 8, 2016 · 11 pts
Yeah, I can see how you might be a bit confused as to what the hell was going on. Haha. I did not know my web guy linked it to that page. That's a VASTLY different compound, with no cognitive benefits that I can think of
Comment · Thu, December 8, 2016 · 40 pts
I just fired him for you srubek. His family with have no presents for Christmas this year.
Comment · Thu, December 8, 2016 · 15 pts
Always keep peptide in the fridge, as that is where they are most stable. They are MORE stable as a lyophilized powder in the vial, and become LESS stable once you mix them with water. However, some smaller sequence pept
Comment · Thu, December 8, 2016 · 3 pts
That's debatable. There is no human data on this one. So treat it as you would any other brand new nootropic compound with no human research behind it.
Comment · Thu, December 8, 2016 · 13 pts
Correct. The sequence was wrong. We attempted to use a lab in China to supply us P21 when our initial lab ran out of the amino acid we needed. This lab made us fake P21, with alanine instead of adamantane. So we rejected
Comment · Thu, December 8, 2016 · 6 pts
I personally use nasal.
Comment · Thu, December 8, 2016 · 6 pts
No, Orexin-A is a long sequence. So it is not as stable as Semax, P21, and Selank. If we premade nasal sprays, they would not be as potent after shipping. So the vials we sell on the site are all tear-off vials, allowing
Comment · Thu, December 8, 2016 · 15 pts
Simplicity. Nobody should be IVing anything. It's too dangerous. I don't even IM. Subcutaneous is all I will do.
Comment · Thu, December 8, 2016 · 3 pts
>That being said, it produces a histamine reaction from being taken intranasally...for starts *CAN, in me, a person with a histamine disorder. So weigh that out as well. Me getting histamine reactions from things is not
Comment · Thu, December 8, 2016 · 3 pts
They are being made right now. I did not realize we ran out. It's like a madhouse here right now.
Comment · Thu, December 8, 2016 · 8 pts
You don't wake up sleep-deprived every day? Amateur! In all seriousness, it shows most promise as a wakefulness enhancer when you are sleep deprived. If you are getting enough sleep every day, then it's probably not goi
Comment · Thu, December 8, 2016 · 3 pts
Soon. I guess we only got a very small shipment in. So we are waiting on the larger one to arrive.
Comment · Thu, December 8, 2016 · 13 pts
Always the fridge, in both forms. Colder is always more stable for peptides. Freezer is fine for lyophilized peptides, but NOT once they are mixed with water. Freezing water forms crystals, which rip apart the peptide bo
Comment · Thu, December 8, 2016 · 2 pts
I believe they were trying to keep similar sequences to Cerebrolysin. So the MOA should be similar, if those sequences actually reach the brain via oral ROA. All I am seeing are effect studies, not pharmacokinetic studie
Comment · Thu, December 8, 2016 · 5 pts
Probably ours. Our new bank is very strict with filtering cards.
Comment · Thu, December 8, 2016 · 1 pts
We won't run out for at least a week at this rate. So it should be fine. We have more of both being made, though. It's not going away.
Comment · Thu, December 8, 2016 · 3 pts
My pleasure!
Comment · Thu, December 8, 2016 · 1 pts
Can't really say, as they are both very new.
Comment · Thu, December 8, 2016 · 3 pts
Nope, that ship has sailed, unfortunately. You can thank all the people committing fraud for that. We had over $10K in fraud because of gift certificates. So we had to remove that option.
Comment · Thu, December 8, 2016 · 24 pts
The answer to that is no. Please do not buy it.
Comment · Thu, December 8, 2016 · 16 pts
This is a very advanced nootropic peptide, with very little research behind it. Please do not consider it if you are not comfortable with the risk, and have researched extensively. This is not like Alpha Brain.
Comment · Thu, December 8, 2016 · 1 pts
You can still use it on ND.
Comment · Thu, December 8, 2016 · 8 pts
It's my company. I was being facetious. I would prefer people not purchase this product unless they have researched it, and fully understand the risks associated. It's a new compound with no human research. It should be
Comment · Thu, December 8, 2016 · 3 pts
Some people might get that, as the bank is in China. If you are not getting that, and the card is still being denied, it's probably our end denying it.
Comment · Thu, December 8, 2016 · 2 pts
I can't really say for sure, as there is not a lot of pharmacodynamic data. However, I do not see any obvious reasons they would interact poorly. That does not mean they won't, though.
Comment · Thu, December 8, 2016 · 2 pts
I did tag it. If you are not using "subreddit style" then you see it as NSFW. However, everyone else sees it as "High Risk" when using the style sheet for the subreddit. It's how we tag all high risk posts.
Comment · Thu, December 8, 2016 · 3 pts
It's already N-acetylated and C-amidated.
Comment · Thu, December 8, 2016 · 1 pts
I PMed you.
No!!!! You can't just say, "Ohh, the active sequence in P21 is DGGL, so let's just sell powdered DGGL!" Pharmacodynamics do not work like that! That would be like saying, "Ohh dopamine is good. Let's sell powdered dopami
Replying to FW900 · Probably safer than Cerebrolysin. No concerns over prions, less risk injecting it subcutaneously vs IM or IV, not loaded with vitamins. This would be perfect to have as a spray bo…
Damn guys, I just put it up on the site last night. There is already a post about it? Haha. I am only on my second dose of it. It's very hard to convert the rat dosages in the study to human dosages, because they never
Replying to Jackolysis · Not really enchanced it's more of a see below.
It was enchanted by a woodland fairy. No, it was based off the mechanism of Cerebrolysin. They found out CNTF mediated the neurogenetive effects of Cerebrolysin, then used epitope mapping to find the most potent sequenc
Replying to roybo · Is there any research on p21? The search term "p21" gets over 31k hits on pubmed. The p21 page on wikipedia refers to some massive protein that has something to do with cancer. Ca…
You are looking at the wrong P21. There are two compounds commonly referred to as P21.
Replying to Synzael · Okay.. It's a lot different. Semax has been shown to modulate the expression of TKRB (and it's a sub sequence of ACTH) and P21 is based off of cerebrolysin. Mephedrone is based off…
What you talking about, Willis? This sub was here long before I came around. I may have gotten interested in neurochemistry because of MDMA and depression. However, this sub did not spawn from that. But your argument st
I always take Semax with P21, to counter the slight tired feeling it can give. I wonder what peptide in Cerebrolysin is leading to the attention effects you are describing? There are only a few ones in high enough concen