Comment · Thu, December 8, 2016 · Ceretropic & Nootropics Depot
What they were answering
c0bjasnak3 · 2 points
Are you planning to make a nasal version of orexin? How stable is it?
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
No, Orexin-A is a long sequence. So it is not as stable as Semax, P21, and Selank. If we premade nasal sprays, they would not be as potent after shipping. So the vials we sell on the site are all tear-off vials, allowing people to mix themselves.
Comment · Wed, December 7, 2016 · 7 pts
Yes, we ship most packages out that are received before 4pm Phoenix time. There is a reason we waited till today to do it, since Wednesdays are ND's slowest day during the week. So my team is ready for an increase in Cer
Comment · Wed, December 7, 2016 · 3 pts
That's good to know! I'll have to read up on Suvorexant.
Comment · Wed, December 7, 2016 · 7 pts
It will be a regular offering. We might occasionally run out of sprays, till we make more. However, we have plenty of raw peptide.
Comment · Wed, December 7, 2016 · 11 pts
Roger that. I'll put it on the list.
Comment · Thu, December 8, 2016 · 16 pts
Wrong P21. That's a completely different compound. This is the P21 we are selling: http://imgur.com/a/mwkTy It's a an N-acetylated peptide with the amino sequence DGGL, which is aspartate-glycine-glycine-leucine, with
Comment · Thu, December 8, 2016 · 5 pts
That's the wrong P21 srubek!
Comment · Thu, December 8, 2016 · 5 pts
Negative, no human studies. We are the only ones to ever really synthesize it in any real quantities. N-PEPT-12 is just an attempt to make an orally bioavailable version of the peptides from Cerebrolysin, but I do not s
Comment · Thu, December 8, 2016 · 8 pts
Haha, that defeats the purpose of trying to avoid confirmation bias altogether.
Comment · Thu, December 8, 2016 · 11 pts
I saw that. It's fixed now. My web guy thought he was being helpful, not knowing it was a completely different P21. There is no Wikipedia entry for this P21.
Comment · Thu, December 8, 2016 · 3 pts
Yeah, that's fixed now. My web guy did not know this P21 did not have a Wikipedia entry.
Comment · Thu, December 8, 2016 · 5 pts
My histamine issues occasionally happen with both nasal and sub-Q. I have not tried it IM, though.
Comment · Thu, December 8, 2016 · 4 pts
Studies usually use 50-100mcg nasally (1mcg/kg).
Comment · Thu, December 8, 2016 · 4 pts
Studies have shown that nasal ROA is over 10X as effective as IV. So nasal seems to be the most effective ROA. 1mcg/kg was used in the study for nasal.
Comment · Thu, December 8, 2016 · 8 pts
I'll definitely look into it. It seems interesting. I'll have to see how economically feasible it is.
Comment · Thu, December 8, 2016 · 11 pts
Yeah, I can see how you might be a bit confused as to what the hell was going on. Haha. I did not know my web guy linked it to that page. That's a VASTLY different compound, with no cognitive benefits that I can think of
Comment · Thu, December 8, 2016 · 40 pts
I just fired him for you srubek. His family with have no presents for Christmas this year.
Comment · Thu, December 8, 2016 · 15 pts
Always keep peptide in the fridge, as that is where they are most stable. They are MORE stable as a lyophilized powder in the vial, and become LESS stable once you mix them with water. However, some smaller sequence pept
Comment · Thu, December 8, 2016 · 3 pts
That's debatable. There is no human data on this one. So treat it as you would any other brand new nootropic compound with no human research behind it.
Comment · Thu, December 8, 2016 · 13 pts
Correct. The sequence was wrong. We attempted to use a lab in China to supply us P21 when our initial lab ran out of the amino acid we needed. This lab made us fake P21, with alanine instead of adamantane. So we rejected
Comment · Thu, December 8, 2016 · 6 pts
I personally use nasal.
Comment · Thu, December 8, 2016 · 15 pts
Simplicity. Nobody should be IVing anything. It's too dangerous. I don't even IM. Subcutaneous is all I will do.
Comment · Thu, December 8, 2016 · 3 pts
>That being said, it produces a histamine reaction from being taken intranasally...for starts *CAN, in me, a person with a histamine disorder. So weigh that out as well. Me getting histamine reactions from things is not
Comment · Thu, December 8, 2016 · 18 pts
I would not purport it as safe, since we don't have human studies behind it. I see no evidence to say it is unsafe, but that's not the same thing as safe. I tagged it as high risk because of how new it is.
Comment · Thu, December 8, 2016 · 3 pts
They are being made right now. I did not realize we ran out. It's like a madhouse here right now.
Comment · Thu, December 8, 2016 · 8 pts
You don't wake up sleep-deprived every day? Amateur! In all seriousness, it shows most promise as a wakefulness enhancer when you are sleep deprived. If you are getting enough sleep every day, then it's probably not goi
Comment · Thu, December 8, 2016 · 3 pts
Soon. I guess we only got a very small shipment in. So we are waiting on the larger one to arrive.
Comment · Thu, December 8, 2016 · 13 pts
Always the fridge, in both forms. Colder is always more stable for peptides. Freezer is fine for lyophilized peptides, but NOT once they are mixed with water. Freezing water forms crystals, which rip apart the peptide bo
Comment · Thu, December 8, 2016 · 2 pts
I believe they were trying to keep similar sequences to Cerebrolysin. So the MOA should be similar, if those sequences actually reach the brain via oral ROA. All I am seeing are effect studies, not pharmacokinetic studie
Comment · Thu, December 8, 2016 · 5 pts
Probably ours. Our new bank is very strict with filtering cards.
Comment · Thu, December 8, 2016 · 1 pts
We won't run out for at least a week at this rate. So it should be fine. We have more of both being made, though. It's not going away.
Comment · Thu, December 8, 2016 · 3 pts
My pleasure!
Comment · Thu, December 8, 2016 · 1 pts
Can't really say, as they are both very new.
Comment · Thu, December 8, 2016 · 3 pts
Nope, that ship has sailed, unfortunately. You can thank all the people committing fraud for that. We had over $10K in fraud because of gift certificates. So we had to remove that option.
Comment · Thu, December 8, 2016 · 24 pts
The answer to that is no. Please do not buy it.
Comment · Thu, December 8, 2016 · 16 pts
This is a very advanced nootropic peptide, with very little research behind it. Please do not consider it if you are not comfortable with the risk, and have researched extensively. This is not like Alpha Brain.
Comment · Thu, December 8, 2016 · 1 pts
You can still use it on ND.
Comment · Thu, December 8, 2016 · 8 pts
It's my company. I was being facetious. I would prefer people not purchase this product unless they have researched it, and fully understand the risks associated. It's a new compound with no human research. It should be
Comment · Thu, December 8, 2016 · 3 pts
Some people might get that, as the bank is in China. If you are not getting that, and the card is still being denied, it's probably our end denying it.
Comment · Thu, December 8, 2016 · 2 pts
I can't really say for sure, as there is not a lot of pharmacodynamic data. However, I do not see any obvious reasons they would interact poorly. That does not mean they won't, though.
Replying to FW900 · MYASD, do you plan on releasing a P21 spray offered on the Ceretropic website in the future?
Yes. We are just waiting till the new glass nasal spray bottles to arrive. There will be P21 sprays, along with Acetyl Semax and Acetyl Selank sprays.
Replying to yallapapi · I agree its not ideal, but I'd like to make a spray with semax, selank and P21 all mixed into one so I can just spray them together and not have 3 different sprayers.. If you've go…
No, you can do that. Just be aware that mixing different peptides into the same solution can reduce stability. There are differing charges and amino acid terminals, that can speed up the breakdown of the peptide bonds. I
Replying to crogenroler · I bet they could really sell the hell out of a sampler packet of "Memantine, Semax/Selank, P21, Super Rodiola and coluracetam. maybe a bit more pricy, but.... however, the current …
I will think about a nasal spray sampler.
Replying to edefakiel · Do you think it is safe to order Semax, Selank or P21 here in the south of Spain? If not now, during the summer, at winter at least.
For the most part, yes. It really depends on your customs and postal system, though. If they leave it out in very high heat, then it might be more of an issue. However, it is pretty stable. Only very high heats affect it
Replying to Debonaire_Death · It would be great if you could offer a peptide sampler that has a specific peptide in its generic, acetylated, and amidated versions. A lot of people find that only one type agrees…
We just started that with Semax. We will probably do it with Selank (We have NA-Selank Amidate on the way too). I can see what we can do with Epitalon. We would have to get smaller vials for it, but that is doable.
Replying to shtuf · Is this why you go with domestic suppliers for your custom peptides like P21, Selank, and Semax? The purity is assuring, but it sure would be nice to get some of these produced in …
We are going to start synthesizing our peptides in-house soon. We am going to purchase all the equipment, and hire a peptide chemist. That is the only scenario that makes sense going forward. We are spending hundreds of