Comment · Wed, December 11, 2013 · Ceretropic
Expanding hippocompal volume with NSI-189 and Tianeptine.
Original post in this thread
Psychoactivekittykat · 15 points
Tianeptine reduces stress-induced reductions in hippocampal volume. NSI-189 IIRC continuously expands hippocompal volume. IIRC increased, continuous expansion of the hippocampal volume can lead to drastic improvements in cognitive performance, working memory, depth perception, and motor-skill function.
NSI's expanding properties, and tianpetines reduction reducing properties, when combined, could they lead to even more hippocampal volume expansion? Leading to more profound effects?
* http://en.wikipedia.org/wiki/NSI-189
* http://investor.neuralstem.com/phoenix.zhtml?c=203908&p=irol-newsArticle&ID=1708123&highlight=
* http://clinicaltrials.gov/ct2/show/NCT01310881?term=neuralstem&rank=1
* http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902200/
What they were answering
paliphrey · 1 points
Complete analogues are without a doubt harder to develop and demand further research, so your solution is perhaps okay – although it does sound like some sort of external evergreening. I doubt it will legally plausible.
A very slight change to a compound may still drastically change its interaction with the body, even if it (only partially, in most cases) retains receptor/ligand binding affinity for a specific receptor.
However, best of luck to you. Don't get into any trouble, now! :)
u/MisterYouAreSoDumb · Ceretropic
We are definitely in uncharted territory. We are going to have to take it one step at a time, and see what risks are worth it, and which ones are not. I'm weighing in all the variables.
It will be interesting, that is for sure.