Expanding hippocompal volume with NSI-189 and Tianeptine.

Comment · Tue, December 10, 2013 · 11 pts

We may be coming out with an NSI-189 analog soon. I am going to have such a large and sexy hippocampus.

Comment · Tue, December 10, 2013 · 6 pts

Yes, Ceretropic will. We are calling it NSI-189F for now. We have the lab ready to make it. We just need to give the go ahead to do it. It will be a premium nootropic, and run around $100 for a two month supply. There a

Comment · Tue, December 10, 2013 · 3 pts

Our analog should have the exact same effects as NSI-189, but will not be subject to the patent limiting the sale. That is why we made it. It should also be slightly more lipophilic. We did not have the coluracetam cust

Comment · Tue, December 10, 2013 · 1 pts

Yes, and very frustrating.

Comment · Tue, December 10, 2013 · 3 pts

Jason came up with the structure, with some input from the lab. We have a lot of new chemical structures we'll eventually be synthesizing and releasing.

Comment · Tue, December 10, 2013 · 1 pts

We modified the chemical structure to get around the patent, but not change the affinities.

Comment · Tue, December 10, 2013 · 5 pts

There is always that risk. We have a lot of backup plans in place in case things like that happen, though. Our small size gives us the flexibility to make large changes quickly. Plus, I do not think we are going to be on

Comment · Wed, December 11, 2013 · 2 pts

We have not consulted a lawyer. I am not sure there is enough demand for this particular product for us to warrant that kind of cost. I may speak to some friends of mine that deal in patent law.

Comment · Wed, December 11, 2013 · 1 pts

We are basing our decisions on a lot of variables. Obviously the compound has to be economically feasible first and foremost. Not very many people would pay $100-200 for a month supply of a given compound. But the main d

Comment · Wed, December 11, 2013 · 1 pts

It is a possibility. Until we get it in, we are not going to be sure of the solubility. So it might not even be able to be put into a solution. One thing we have learned so far is that you cannot trust the solubility num

Comment · Wed, December 11, 2013 · 2 pts

We have an extremely well fed orangutan, surrounded by O-chem books. He also has access to Google. So we should be good to go! In all seriousness, we are only making slight modifications to the molecule, that will not a

Comment · Wed, December 11, 2013 · 3 pts

We are definitely in uncharted territory. We are going to have to take it one step at a time, and see what risks are worth it, and which ones are not. I'm weighing in all the variables. It will be interesting, that is f

Comment · Tue, January 28, 2014 · 2 pts

No, it stands for NSI189-Fantastic! Or was it fluoro? Hmm, I guess we'll just have to wait and see.

Comment · Tue, January 28, 2014 · 2 pts

Yes, we've checked. The modification to the molecule that we have done does not affect the binding of the key functional groups. In fact, it may even lead to increased lipid solubility, which could mean lower doses or l