What happened to NSI-189?

Comment · Tue, February 17, 2015 · 3 pts

I wonder where all that NSI-189 that was not sold is... Where on earth would large amounts of it still exist? Hmmm

Comment · Tue, February 17, 2015 · 3 pts

They were upset because we were piggybacking off the name "NSI-189." Jason and I came up with some cool NSI-189 analogs. I'm sure we could synthesize it, and call it CRE-1, or something like that.

Comment · Wed, February 18, 2015 · 4 pts

Ehh, I see that they have to defend their intellectual property. They think they have a home run in NSI-189, and do not want to jeopardize that.

Comment · Wed, February 18, 2015 · 2 pts

Memantine is off-patent in April 2015. It's not worth their time. NSI-189 is still not approved, and could be a billion dollar drug. So the difference is one is at the beginning of the drugs life cycle, and the other is

Comment · Wed, February 18, 2015 · 1 pts

Well I would like to think we would assign numbers with actual meaning to them. Haha

Comment · Wed, February 18, 2015 · 1 pts

It was just an analog of NSI-189.

Comment · Thu, February 19, 2015 · 1 pts

It's also to do with the size of the companies. Neuralstem is only worth $100 million. A lot, but nothing compared to Actavis at $91 billion. Actavis does not give a shit about us. We are like single celled organisms to

Comment · Thu, February 19, 2015 · 1 pts

Yeah, but we are not selling XR. The new patent only covers the delivery system, not the drug itself. These kind of shady patent issues are why they are worth $91 Billion. You don't get to that point by being the nice gu

Comment · Tue, February 24, 2015 · 2 pts

I've known about Dihexa for over a year. I have even tried to get it synthed a while back. It's a 14 mer peptide, so it is very expensive. FGL, which is a 15 mer peptide, is even more promising. However, it too is too ex

Comment · Tue, February 24, 2015 · 2 pts

Dihexa looks to be about a 25mg dosage, based on rat studies. FGL is 30mg threshold, and 100mg ideal. I'd have to charge like $300/g for Dihexa. FGL is not even in the realm of possibility with the pricing I am currently

Comment · Tue, February 24, 2015 · 1 pts

I'll see if I can find them tomorrow. It's 8pm, and my girlfriend is already wondering where I am. Not like I leave the office before 8pm usually anyway... Message me tomorrow to remind me, if you have not already found