Comment · Sat, March 16, 2013 · Ceretropic
Can we have a post for the beginners for understanding NMDA nootropic action?
Original post in this thread
[deleted] · 21 points
I'm new. AMPA receptors make a lot more sense than NMDA receptors when it comes to enhanced cognition, but they both seem crucial.
With NMDA receptors. Antagonists, agonists, and modulators all seem to have a complex role that I don't understand when it comes to cognition enhancement.
For instance Ketamine and PCP are an antagonistic yet so is Memantine and huperzine-A . Some cause Olney's Lesions and others are for Alzheimers.
Is there a NMDA explanation that is more straightforward out there?
Can somebody lay out NMDA for those in the dark like me?
What they were answering
[deleted] · 1 points
What would be the novel cAMP accelerator to take? Can I take it with Phenylpiracetam and Noopept and oxiracetam? (I've actually tried all three at the same time and it was great.
u/MisterYouAreSoDumb · Ceretropic
Most people use artichoke extract for cAMP, forskolin for PDE-4 inhibition, then something in increase dopamine like caffeine or PEA. Phenylpiracetam would be good because it will increase dopamine from the PEA structure, and modulate NMDARs. Then you could add in an AMPAR like aniracetam, and noopept for NGF/BDNF.