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Nootropics Depot now reducing pill sizes
Replying to Professional_Cost · I've bought the ND phenibut capsules several times and I'm cool with the change. A few questions though. What's the margin of error of the amount of phenibut in each capsule? If I…
We plan for a 5% overage on capsules. So more often than not they are a bit over the target weight. Then we follow a tightened form of the USP guideline on capsule variation. So they have to fall within a 10% variation up/down from the target weight. Most manufacturers plan to ex…
Nootropics Depot now reducing pill sizes
Replying to abadhe99 · Thanks for this
My pleasure!
Nootropics Depot now reducing pill sizes
We have a lot more options on tooling/capsule size now. So wherever possible, we are reducing the size of the capsules to reduce the amount of filler we need to use. You will notice many products getting put into smaller capsules across our whole line. The amount of active ingred…
Alcohol Defense Review
Replying to iwantmyownname · Interesting never knew peppermint could be anti-emetic, always just associated it with digestion and the intestines. Thanks!
Yeah, peppermint oil is a potent antiemetic. It's mostly the menthol content leading to those effects.
Lion's Mane 8:1 - General Malaise
Replying to full_silver · I'm taking those other 3 as well in conjunction. The 5-AR effects should be temporary though and come back after cessation right, it's not permanent like shit like finasteride rig…
Correct, they should be temporary. Finasteride is a much more potent one; inhibiting DHT by up to 70%. Ethanol extracts of reishi seem to be more potent than other mushrooms at 5-AR effects; in rats at least. I am actually not seeing anything showing lion's mane has 5-AR effects.…
Alcohol Defense Review
Replying to iwantmyownname · Do you know which of the 5HT3 antagonists you are going to use?
We will probably end up using peppermint.
5HTP works better without ECGC?
Replying to voltairebear · I might be mistaken but melatonin taken as a supplement does not cross the blood brain barrier, rendering it useless for some people (including me).
Melatonin certainly does cross the blood brain barrier. https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1471-4159.1980.tb11272.x
DynaMAX Methylliberine / Caffeine cross tolerance?
Since methylliberine is potentiating the caffeine, it might affect tolerance. I have not noticed it too much, though. However, I react well to caffeine. The caffeine release is pretty balanced over the course of 8 hours, with a bit of a bias toward the 2-3 hour mark, due to the d…
Fake magnesium citrate from Bulk Supplements?
Replying to Nick315 · No I had not, but have now. Thanks for the links. In the 2 years since then has there been much difference in the reliability of Labdoor in your experience? With so little credibi…
I have not seen anything that would indicate they have changed for the better.
Lion's Mane 8:1 - General Malaise
Sometimes certain things are just not right for people. I would not force yourself to keep taking something that gives you side effects. You are either sensitive to the possible 5-AR effects, or you are sensitive to the kappa opioid compounds in lion's mane. Consider that this ex…
PEA and cannabis redundant?
No, they act on different receptors. We have a blog on it. http://nootropicsdepot.com/articles/palmitoylethanolamide-and-its-pain-management-benefits/ We should expand on and update this blog. It has been a while since we talked about palmitoylethanolamide. I will speak to my tea…
Fake magnesium citrate from Bulk Supplements?
Replying to Nick315 · And yet Labdoor gives their Green Tea Extract their top ranking out of 25 tested, though their labeling got a lower score. And their CoQ10 was the top ranked.
Have you read my rants on LabDoor as well? https://www.reddit.com/r/Nootropics/comments/5f5hgw/is_there_a_lab_that_tests_and_reports_on/dajeyfx/ https://www.reddit.com/r/Nootropics/comments/7liwtb/labdoor_bacopa_rankings/ The results I spoke about above were not even done in my l…
Any chance of adding 10mg Noopept capsules to the product line?
Replying to Professional_Cost · Don't you have one of those industrial capsule machines like [https://youtu.be/HoKjepJ4osU?t=125](https://youtu.be/HoKjepJ4osU?t=125) ? What kind of machine do you guys use to fill…
Yes, but the automatic machine takes a full 4 hours of changeover time for cleaning. Usually it only makes sens to run that one for runs of 500,000 to 1,000,000 capsules at a time. The semi-auto machines are used for smaller runs. Plus, you have a fixed cost for every capsule, an…
Anyone Tried Cinnamyl-Piracetam?
Replying to Debonaire_Death · I'm tempted to try a larger-scale synthesis of this. I have a hot plate with magnetic stirrer, and plenty of piracetam. There's reagent-grade cinnamaldehyde for sale in half-liter …
https://scholar.google.com/ I assume the alcohol wash/recystalization would work for a cinnamyl-piracetam as well. It will be interesting to see how it works for you!
ND container/advertisement rebrand looks good
Thanks for the feedback! We should have all our Amazon product images updated shortly. We are also enabling enhanced brand content on a lot of our listings there, and getting our faster sellers back into Amazon's warehouses for Prime shipping. We will still have the whole catalog…
Fake magnesium citrate from Bulk Supplements?
They literally don't do any testing, and will never give anyone lab analysis that asks for it. This has been the same for years and years. Anyone can try it. Email them as ask for a COA and analysis from any one of their products. They will just stop responding to you. Furthermor…
Anyone Tried Cinnamyl-Piracetam?
Replying to Debonaire_Death · So do you think people dropping this on raw piracetam and waiting for it to dry are making anything, or getting a placebo effect? Frankly, I could see direct contact with high con…
I doubt dropping cinnamon oil on piracetam powder would be creating much. Heating a concentrated solution of cinnamon oil and piracetam might be a different story.
Any chance of adding 10mg Noopept capsules to the product line?
Replying to mercnz · have you considered doing really small pills and doing something like 100/50 of caffeine/theanine... so that you could take 2 or 3 if you want or just take 1..
Then encapsulation costs start making the economies of scale not make sense. We could, but there is a fixed cost to each capsule and the labor to fill each that would make those smaller doses not as economically attractive to most people.
Anyone Tried Cinnamyl-Piracetam?
Replying to Debonaire_Death · /u/misteryouaresodumb, this making any sense to you? I've tried working out an arrow-pushing mechanism for the reaction, but I'm no organic chemist. Apparently it's supposed to giv…
Cinnamaldehyde is very reactive. So it might react just in solution. I will have to speak to my lab director about it to confirm. I think perhaps heating them both in solution would be enough to cause the reaction between the cinnamaldehyde and the amide grouping on the piracetam…
is it still safe to take NAC before drinking and then alcohol defense after?
Yes, I do that often if I am going to be drinking for long periods, like a beer festival. That way you are protected while you are drinking, and after you are done.
The effects of Thymoquinone (TQ; 6mg/kg/day, Sub-Q), from Black Seed, on prostate cancer growth in mice
Replying to ivres1 · Black Seed Oil at 5% TQ with the recommend dosage of 200mg per days get you 10mg of Thymoquinone orally. Correct me if I'm wrong, but assuming the extract is 5% you would need to…
You're looking at 800-900mg of a 5% thymoquinone extract to match the above study's dosage in mice. That doesn't mean that is the ideal dose for humans, though. This was a study meant to show statistical significance in their model. So the ideal dose for humans could be lower tha…
Immune stack
Yes, that's one of the next ones we are releasing with the Sleep Support stack. The next two stacks are going to be two stacks in our "Essential Stack" series, like DynaMAX. Those are optimized/enhanced versions of specific things. DynaMAX is an enhanced caffeine. The next two ar…
Alcohol Defense Review
Thanks for the feedback! The feeling you had the next day was likely a tired feeling due to the glycine. We put glycine in the stack last minute because some people were unable to sleep on the formula before. The glycine definitely made sleeping easier, but it does cause some peo…
I recently bought from nootropics depot
Replying to meningitis217 · The mail came it was not delivered. Your team emailed me, they are resending it. I would like to thank you and your team for being so kind. I will be ordering from you guys again.
It's our pleasure! Glad we could get you taken care of.
I recently bought from nootropics depot
Replying to meningitis217 · Thank you. Do you want me to reply to this comment to let you know if it comes or not?
You can, but my support team would be best to run point on it. Have you emailed them yet? I linked them this thread so they know what is going on.