Comment · Sat, January 9, 2021 · ND Owner
N. DEPOP NEEDS to look into things that work on EAAT2 glutamate pump expression in central nervous system, therefore reducing glutamate toxicity.
Original post in this thread
squirtking33 · 28 points
I suffer with some awful persistent infections that, when under stress, create an opportunistic environment for latent bacterial, viral and fungal infections to take a hold. Borreliosis has, however, been the worst infection I’ve had to fight. No, I’m not talking about Lyme Disease, which is a fraudulent case definition of a single bad knee, falsified by the likes of Wormser, Weinstein, Halaprin, Klmepner, Steere, Shapiro, etc., however, I won't get into that whole ordeal. In any case, neuroorreliosis is known to cause increased glutamate, Ammonia, in some cases; and especially Quinolinic Acid in the brain, a potent excitatory neurotoxin. Nothing had worked for me except one thing and that was the antibiotic ceftriaxone (Rocephin) even if it may not kill even half of viable spirochetes in vitro.
Ceftriaxone was amazing for my pain, brain sparks, probably due to QUIN; verbal fluidity, brain fog, headaches, anxiety and eradicated depression. No other nootropic or drug, had cleared my brain of noise and anxiety better than ceftriaxone, now I’m sure it was partly to do with it helping to clear out neuroborreliosis but its underlying mechanisms of actions are interesting. Plu,s I h…
What they were answering
4SCOOPSCMON · 1 points
I just saw this post, and recently have been wondering if my brain is too exited because I have noticed anxiety like symptoms even in positive situations and becoming extremely exited by things that I find interesting, meaning that when I speak about something I like, I get physically and mentally way too excited. I also think I remember something about glutamate/GABA relationship to autism and schizophrenia which I have in my family.
I would like to try to reduce glutamate activity and see if the situation improves because the GABA way usually makes me depressed (not even taking in account down regulation)
Would the ways described in this thread be a good idea for me to try out? And how did you guys progress on a product targeting this?
u/MisterYouAreSoDumb · ND Owner
It's only been a month. R&D takes a lot more time than that. I wouldn't expect meaningful movement on something till later this year.
What all have you tried to address it? Have you tried things like L-theanine and lemon balm yet?