Comment · Fri, April 2, 2021 · ND Owner
N. DEPOP NEEDS to look into things that work on EAAT2 glutamate pump expression in central nervous system, therefore reducing glutamate toxicity.
Original post in this thread
squirtking33 · 28 points
I suffer with some awful persistent infections that, when under stress, create an opportunistic environment for latent bacterial, viral and fungal infections to take a hold. Borreliosis has, however, been the worst infection I’ve had to fight. No, I’m not talking about Lyme Disease, which is a fraudulent case definition of a single bad knee, falsified by the likes of Wormser, Weinstein, Halaprin, Klmepner, Steere, Shapiro, etc., however, I won't get into that whole ordeal. In any case, neuroorreliosis is known to cause increased glutamate, Ammonia, in some cases; and especially Quinolinic Acid in the brain, a potent excitatory neurotoxin. Nothing had worked for me except one thing and that was the antibiotic ceftriaxone (Rocephin) even if it may not kill even half of viable spirochetes in vitro.
Ceftriaxone was amazing for my pain, brain sparks, probably due to QUIN; verbal fluidity, brain fog, headaches, anxiety and eradicated depression. No other nootropic or drug, had cleared my brain of noise and anxiety better than ceftriaxone, now I’m sure it was partly to do with it helping to clear out neuroborreliosis but its underlying mechanisms of actions are interesting. Plu,s I h…
What they were answering
whatevergotlaid · 1 points
If I am having problems with glutamate causing anxiety, would starting with L-carnosine and Magnolia bark be enough to illuminate me to the mechanisms causing my problem? In other words, do I need to take this whole stack, or can I start with the first two and see if they have some effect on my biology? Or does the entire stack work together?
Can I develop tolerances or further up/down regulation that isn't wanted with the two I mentioned?
u/MisterYouAreSoDumb · ND Owner
You can certainly start with carnosine and magnolia bark to see how you respond. It's good slowly adding things in anyway, rather than jumping straight into a larger stack. That way you can assess how each one is affecting you.