Comment · Mon, July 11, 2016 · Ceretropic & Nootropics Depot
Fasoracetam
Original post in this thread
iamgoingbald666 · 26 points
Hello /r/Nootropics
I have a couple of general questions regarding Fasoracetam. I searched this sub (I think I read every topic and most of the comments) and a couple other sites regarding info on this substance. However, it never hurts to get more anecdotes. So as for the questions:
1. What have you found to be the most effective dose (dose AND # of times dosed a day)?
2. In addition, what RoA (route of administration) have you found most effective (sublingual or oral)?
3. Have you found it more beneficial taken on an empty stomach or with food?
4. What are the acute and long term effects for you?
I have read anecdotally that Fasoracetam has given people a mood, concentration, and focus boost (general motivation boost, the reason I want to try it). I have also read that it helps with anxiety as well (this is not as much of a problem for me, and not the reason I am looking into the substance, but I digress). Additionally, the effects are supposedly increased as the substance is used more.
Essentially I am looking for any and all anecdotes for this substance; good or bad.
What they were answering
vapefker · 3 points
It is NOT directly binding to GABAb, and is not a GABAb antagonist like many state.
Thanks for pointing this out, as many people falsely claim it to be. One would assume a GABAb antagonist would promote anxiety and negatively effect ones mood. Most people report a mood uplift after tasking Fasoracetam, so it's obvious not an antagonist.
However, what is your take on using Fasoracetam to help prevent Phenibut tolerance? In theory, Fasoracetam upregulating GABAb should potent Phenibut.
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
Fasoracetam does up-regulate GABAb. So it can help with that side of Phenibut tolerance. However, Phenibut also stimulates dopamine receptors and antagonizes β-phenethylamine. So it will not affect those tolerance levels. It certainly helps with the GABA side of things, though.