Comment · Wed, January 28, 2015 · Ceretropic
Low dose DXM as a nootropic?
Original post in this thread
Sayitaintsoooooooo · 4 points
I've been wondering about this for a while. I understand there are benefits and drawbacks to frequent DXM use including potential language issues and derealization. I've tried low dose before but not over an extended period of time but I did notice a large boost in mood and motivation. DXM is a dopamine reuptake inhibitor as well as a decent anti depressant but isn't very well understood obviously since studies on it are only primarily focused on it's anti-tussive properties.
Does anyone have any thoughts/experience with DXM as a noot?
What they were answering
Bomb_Jack · 1 points
So when you do that protocol it's just for tolerance reversal, not the other benefits you were writing about.
...But why don't take a dose concurrently the substance you want tolerance to avoid to, for instance?
u/MisterYouAreSoDumb · Ceretropic
No, it gives other effects that are nice. It seems to elevate mood for weeks following use. It might be due to the Sigma-1 agonism. I doubt it is the SRI activities, as I do not find the same effect with other SRIs. However, it could be a combination of mechanisms.
If you want to take something concurrently, I would probably use Memantine. That would be better tolerated for daily use.