Comment · Thu, July 17, 2014 · Ceretropic
Could acid catalyzed hydrolysis of esters/amides be effecting your nootropic experience?
Original post in this thread
DocDimethyl · 8 points
1) Many nootropics have ester or amide functional groups (Noopept, all of the racetams, any peptide derived molecules, etc.).
2) The stomach has a pH of around 2 (HCl).
3) Esters and amides can be cleaved by a proton catalyzed reaction.
So would the bio availability of nootropics be enhanced by taking simple antacids to try to neutralize the stomach acids?
What they were answering
Enersia · 2 points
Your coluracetam is fine..a bit too sweet for my bad teeth..haha. and your DMAA is perfect!
A lot of us loves coffee, maybe it would be a good flavor too.
u/MisterYouAreSoDumb · Ceretropic
Yeah, I think I have been going overboard on sweetening the coluracetam. My taste buds just really do not like the taste of coluracetam, and I try and sweeten it to mask it.
The new DMAA is chocolate vanilla coffee. The one you probably got was pumpkin spiced coffee. People do seem to really like those. Perhaps I will try a coffee based coluracetam batch.