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The story behind the FDA raid of Nootropics Depot

Replying to MrTomen · Thank you for explaining this so clearly. I watched your interview @PricePlow and now this and am grateful. For your work and contribution to this world. For years I've tried to e…

When everything went down with the government, I was instructed by my legal team to say absolutely nothing to anyone about it. That's exactly what we did. We went completely silent on it for two years. This opened the door to conspiracy theories and weird made up theories from pe…

The story behind the FDA raid of Nootropics Depot

Replying to Megatron_McLargeHuge · I though it was about Tianeptine. Or was that a different case?

Tianeptine, adrafinil, piracetam, aniracetam, oxiracetam, phenylpiracetam, pramiracetam, etc. You can read my long comment on it above. We had stopped selling tianeptine years prior to the government coming into our facility, but we were selling racetams and adrafinil on the ND s…

Cognance: waste of money

Replying to MisterYouAreSoDumb · Listen, I know shit can be frustrating. However, rejecting reality because you are upset only hurts you. The idea that everyone's biology is different is not an opinion. It's an ou…

...continued from above... [Placebo responders and nonresponders: what’s new?](https://www.futuremedicine.com/doi/pdf/10.2217/pmt-2018-0054) Some researchers have even tried to select for placebo non-responders to see if they could overcome the placebo effect. The placebo effect…

Cognance: waste of money

Listen, I know shit can be frustrating. However, rejecting reality because you are upset only hurts you. The idea that everyone's biology is different is not an opinion. It's an outright fact. Ask any doctor that prescribes drugs if all their patients react the same way, and they…

Taking oleamide with fat?

Replying to MuscaMurum · Yes, I know it's a fat, but that's not my question. Does taking it with a fatty food help absorb it better? It's not uncommon to take fat soluble supplement with fats.

It's not uncommon, but it is wrong. Fat will not help oleamide absorb. Fat will not help most fat soluble things absorb. It's an oversimplification of pharmacokinetics, and an oversimplification of solubility. I've ranted about it for years. Lipid-soluble compounds naturally diff…

Why would 7,8 DHF make me want to end my life?

Replying to [deleted] · [deleted]

Yes, we have something coming out soon that is pretty exciting on that front! It is kind of like a replacement for piracetam, but it hits GABAb as well, so it should have some of that calming effect or aniracetam, too. I really like it.

Black friday sale?

Replying to xnxxnxxxxn · Ordered! 5x 120 Immune Defense + 1x 120 emoxypine because I was so impressed with it so far. Used it this morning actually, emoxpine + aniracetam + coqSOL-CF + ecgc + triple streng…

We put the "You're our number one customer!" as a joke on all orders today. It's from the movie Jingle All The Way. Arnold Schwarzenegger says it to all his customers at the start of the movie, and then accidentally says it to his wife. LOL Yeah, we are VERY busy today. All hands…

Reddit AMA | In-House Lab Edition

Replying to gene_n_tacos · I was very impressed with the dry and wet lab equipment shown on the virtual laboratory. For small molecule nootropics like phenibut and aniracetam for example, you mentioned that …

That depends on how specific or advanced the methods are. I can't divulge the names of our partners, as we are under NDAs, but we have a few different labs we use. We have one partner for our normal basic NMR work. They like running samples through their machine and giving data,…

Poor Quality Aniracetam?

Replying to LimitlessLyfe · I will do this. But I actually want to also compliment nootropics depots' customer service. They reached out to me and took care of the issue.

Ohh good! Glad to hear it!

Poor Quality Aniracetam?

I looked at all the lab documents for the most recent few batches of aniracetam, and everything is perfect. In fact, we are still using the same batch from October 2020 for the aniracetam powder jars on the shelf. We've gotten newer batches in, but they have all gone to capsule p…

Aniracetam no price difference between 500mg tablet vs. 750mg capsule

Costs for aniracetam have gone up a ton, along with pretty much everything else. It looks like we accurately adjusted the tablet pricing, but have not adjusted the capsules and powder pricing yet. Normally we have triggers for when we need to adjust pricing based on a cost increa…

Piracetam restocking?

Replying to peoplearestrangeanna · Well I am glad I got my hands on some. I wanted to try it first, because it has the most research on it, so instead of Noopept I got the Piracetam. And I also got Aniracetam and Co…

This is the best site to track a standard package: https://webtrack.dhlglobalmail.com/ Once it is on its way to Canada, it will be assigned either a Canada Post or TForce local tracking number. You will see that in the "Delivery by Postal provider" on the right side. That will us…

Is polygala a strong enough MAOI that it shouldn’t be combined with aniracetam?

Replying to drunkthrowwaay · Hi MYASD, Do you happen to know, or have an opinion on, whether polygala would have any problematic interactions with an SSRI like escitalopram? I’m wary of serotonin syndrome. A…

Polygala is not a strong serotonergic, so I would not think there would be any issue. Usually serotonin syndrome happens because of the combos of irreversible MAOIs and SSRIs. However, always speak to your doctor before adding new things into your regimen if you are on prescripti…

Is polygala a strong enough MAOI that it shouldn’t be combined with aniracetam?

Replying to MuhammadTheProfit · I'm taking bromantane (reshipped), polygala, and tianeptine sulfate. I take LSD every several weeks and have been wondering if I should take a week or two off before psychedelic us…

Yeah, taking a week off before using something as strong as LSD is always a good idea.

Is polygala a strong enough MAOI that it shouldn’t be combined with aniracetam?

No, it's not something you need to worry about. The main compound in polygala that has MAOI effects is called DISS (3,6'-disinapoyl sucrose). It has less than 0.5% bioavailability. This means it is likely not clinically relevant at reasonable oral doses. https://pubmed.ncbi.nlm.n…

I am a final year medical student. Supplements I take. Feedback on my stack appreciated.

Replying to -keyz_ · >And no, most racetam research comes from very few research groups, most located in Eastern Europe and Russia. Likely all affiliated with each other. I would like to know what u/…

Unsubstantiated nonsense. [Piracetam affects membrane fluidity in the frontal cortex, the hippocampus, and the striatum. It also sensitizes NMDA receptors in the hippocampus](http://www.ncbi.nlm.nih.gov/pubmed/10338103) [Piracetam's effects on the NMDA receptors.](http://www.ncbi…

Fat burning supplements

Replying to [deleted] · Update: damn this is a potent stack. I took 500mg hesperidin, 1x OptimALA, 25mg epicatechin (it's expensive!) and 100mg of berberine (didn't want hypoglycemia), 250mg of milk thist…

Pretty strong, right? It's honestly a really good recomp stack.

the state of Piracetam?

Replying to Kar22 · So does that include Phenylpiracetam and other racetams too?

His most recent study was only on noopept and aniracetam.

the state of Piracetam?

Someone wrote a study on the prevalence of piracetam in products labeled as dietary supplements. Then about 8 months later US customs started holding shipment of piracetam coming into the country. Then COVID-19 happened, and it gave them the perfect excuse to just ignore everyone…

Peter D Cohen strikes again. Be prepared for a new ban, this is the time of Aniracetam and Noopept

Replying to cgcore · This is not good at all, at this rate it seems a very slippery slope, would love to hear /u/MisterYouAreSoDumb opinions on this.

It's the same author that wrote the piracetam one in 2019. What happened to piracetam after that? I think we would be naive to think this won't have a similar effect.

Sleep support causing next morning depressed mood, pessimistic feelings questions....

>I took some NALT with P5P the mornings after, but I really didn’t notice an improvement. I just picked up some regular L-tyrosine, so I’ll try larger doses of this with P5P. Some people get much better effects from L-tyrosine than NALT. I have not figured out why yet, but it is…

Need some help understanding a NAC experience I had

Replying to AwkwardHand · Thank's for the response, I wasn't taking benzos/amphs for 2 years when that happaned. Could you recommend some noots that would be worth a shot in my case? I'm taking bacopa/ash a…

Ohh, it sounded like you had recently quit the benzos and amphetamine. 2 years should be enough time to get back to normal, but they can have some long-lasting effects that linger. >What I want to give a shot now is alpha gpc + aniracetam, tongkat ali, cordyceps, polygala, NMN al…

Feedback on stack: Polygala, NMN, Aniracetam, Tongkat 2%

Replying to Aldarund · Did you do blood tests of testesterone levels regularly ( as it fluctuate ) before and after tongkat ?

Unfortunately not. I was not expecting to react as well as I did. So it was not a controlled experiment by any means. I was given a sample of it at Supply Side West last October, and figured I would give it a shot. I loved it so much, I have basically taken it ever since.

Feedback on stack: Polygala, NMN, Aniracetam, Tongkat 2%

Replying to ianonuanon · Wow man! +37% testosterone status is pretty impressive!!!! (Referring to the second study you posted) . My doubts were unfounded and your assessment was clearly accurate. I am n…

Ohh, don't worry. I figured you were reading that online. I did, too. I figured natural testosterone shit was all bullshit myself, which is why it took me so long to try it. I have completely stopped reading any sites online that summarize scientific data. There is too much misin…

Feedback on stack: Polygala, NMN, Aniracetam, Tongkat 2%

Replying to ianonuanon · In your opinion do any of these imply an effect that is dramatic enough to increase protein synthesis to a noticeable level? Do you feel that someone could grow larger muscles as a…

>In your opinion do any of these imply an effect that is dramatic enough to increase protein synthesis to a noticeable level? Do you feel that someone could grow larger muscles as a result of supplementing with one or all of them? Absolutely. Perhaps not to a massive degree for a…