Comment · Thu, January 14, 2021 · ND Owner
Is polygala a strong enough MAOI that it shouldn’t be combined with aniracetam?
Original post in this thread
ArtificialBrain808 · 7 points
Considering trying to recreate past success I’ve had micro-dosing 5-ht2 antagonists with ndma antagonists for mood/anxiety/depression. Was totally unaware of how ani worked until recently. Got way too content with phenylpiracetam and didn’t really look into the others(besides colur and faso). Effects wise I think these two would be great but wasn’t sure about the maoi issue? I know it isn’t very strong in that regard. If they shouldn’t be combined would it be okay to take them 12 hours apart? I usually take the recommended daily dose of poly all at once(but never over 300mg) would a biggish dose like this cause me any problems with ani in the morning?
What they were answering
drunkthrowwaay · 1 points
Hi MYASD,
Do you happen to know, or have an opinion on, whether polygala would have any problematic interactions with an SSRI like escitalopram? I’m wary of serotonin syndrome. Any thoughts? Love your work btw.
u/MisterYouAreSoDumb · ND Owner
Polygala is not a strong serotonergic, so I would not think there would be any issue. Usually serotonin syndrome happens because of the combos of irreversible MAOIs and SSRIs. However, always speak to your doctor before adding new things into your regimen if you are on prescription drugs.