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Nearly 90% of herbal sports supplements are mislabeled. One in ten contain prohibited substances | The labels of sports supplements are not what they seem to be.
Replying to henryptung · True for "nutrients" as defined in the various classes listed in link, but would note that most of the stuff included in the "supplements" from the article probably don't qualify.
It still qualifies under the 21 CRF 111.70, where you have to set specifications for your product that include "identity, purity, strength, and composition of the finished batch of the dietary supplement, and for limits on those types of contamination that may adulterate, or that…
Nearly 90% of herbal sports supplements are mislabeled. One in ten contain prohibited substances | The labels of sports supplements are not what they seem to be.
Replying to throwaway198990066 · But most supplements don’t have the USP label, and so they’re not held to that standard.
USP just stands for United States Pharmacopeia. The monographs are completely separate from the USP label program. The FDA states that you must meet your product specification, which is what your label claims are derived from. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cf…
Nearly 90% of herbal sports supplements are mislabeled. One in ten contain prohibited substances | The labels of sports supplements are not what they seem to be.
Replying to rdesktop7 · Because those CEOs are not breaking any laws. You can put sugar pills in a bottle, and call it anything you want as long as it's listed as a "supplement".
That's not true. Label claims and concentration are absolutely regulated. [Read 21 CFR 111](https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-111). All supplements have to be at or above label claim, within reason. The USP monograph generally allows for a 10% vari…
Nearly 90% of herbal sports supplements are mislabeled. One in ten contain prohibited substances | The labels of sports supplements are not what they seem to be.
Replying to andydude44 · FDA regulates supplements as if it were food instead of drugs, so they’re not allowed to intentionally mislabel or put known harmful substances in it still, but chemical purity is …
Chemical purity is absolutely regulated. [Read 21 CFR 111](https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-111). All supplements have to be at or above label claim, within reason. The USP monograph generally allows for a 10% variance, so that means supplements s…
.. A new Stanford-led study reveals that turmeric—a commonly used spice throughout South Asia—is sometimes adulterated with a lead-laced chemical compound in Bangladesh, one of the world's predominant turmeric-growing regions. It's a potent neurotoxin considered unsafe in any quantity
Replying to Zequl · u/MisterYouAreSoDumb u/NootropicsDepotCom Is there any way to ensure that the products you are selling are not laced with this product? Have not looked any further into this topi…
Yes, by properly testing it with the appropriate analytical methods. We test every batch with FTIR-ATR, UPLC, HP-TLC, ICP-MS, LOD, and water activity. You would see the lead chromate on the ICP-MS. We test every single batch of every single product on ICP-MS, which goes down to t…
Smokers consume same amount of cigarettes regardless of nicotine levels: Cigarettes with very low levels of nicotine may reduce addiction without increasing exposure to toxic chemicals
Replying to smuzz111 · Pardon my ignorance, but is it the nicotine in cigarettes that is addictive? Or is it a combination of the additives in them?
No, nicotine is not that addictive on its own. It's the MAOIs in tobacco, combined with the nicotine, that lead to the addiction. [Monoamine Oxidase Inhibition Dramatically Increases the Motivation to Self-Administer Nicotine in Rats](http://www.jneurosci.org/content/25/38/8593.f…
People may feel more empathy for dogs than for some of their fellow humans
Replying to [deleted] · [deleted]
I hope eventually you realize that cautionary logic, and trust for those around you, are not mutually exclusive. People are stupid, emotional, under-informed, over-reactionary, and generally ignorant. However, they are all on the same journey you are, and come from different plac…
MDMA 'eases post-traumatic stress':
Replying to starkid · will it have an effect on the heart? like 5-htp?
No, definitely not. It's pretty safe.
MDMA 'eases post-traumatic stress':
Replying to PhedreRachelle · I would like to know how much these rats were given, and for everyone to remember that this was a study on rats and that there are now human trials that can be looked at, which wil…
Yes there are! I have them on my computer. There are rat, mice, primate, and human studies. The dosing ranges anywhere from the human equivalent of 1mg/kg of MDMA to 4mg/kg. These are normal recreational doses. Read through my posts. I cover a lot of it. There is also a ton of ot…
MDMA 'eases post-traumatic stress':
Replying to starkid · what about st john warts?
That is a mild MAOI and SSRI. It actually has an interesting effect of up-regulating serotonin receptors. This will not affect 5-HT production, though.
MDMA 'eases post-traumatic stress':
Everyone seems to have many questions about MDMA. I've typed out more than I care to think about on the subject. If you want some reading, here are my posts and comments to take a look at: http://www.reddit.com/r/DrugNerds/comments/13lp0b/mdma_neurotoxicity_part_1_metabolites/ ht…
MDMA 'eases post-traumatic stress':
Replying to [deleted] · Shitttt D:, well at least there is a solution. Need to find EGCG green tea extract :s thank you for pointing that out!
Just always take 5-HTP with EGCG (Green tea extract).
MDMA 'eases post-traumatic stress':
Replying to [deleted] · > MDMA also lowers your body's ability to produce serotonin. Source?
http://www.ncbi.nlm.nih.gov/pubmed/8496826 __________________________________________________ Also, if you really want a read, go through the post I made a while back on /r/DrugNerds http://www.reddit.com/r/DrugNerds/comments/13lp0b/mdma_neurotoxicity_part_1_metabolites/ Or you c…
MDMA 'eases post-traumatic stress':
Replying to morbidgoldfish · MDMA doesn't give you depression. It depletes your serotonin due to the intense high, causing you to feel depressed or whatever. Depression is more encompassing than that.
What you are describing in down-regulation of the 5-HT receptors. This is a different mechanism to serotonin depletion. MDMA also lowers your body's ability to produce serotonin. The two ring-hydroxylated metabolites of MDMA and it's metabolite, MDA, 2,4,5-trihydroxyamphetamine (…
MDMA 'eases post-traumatic stress':
Replying to dorkrock · MDMA is a serotonin re-uptake inhibitor. Normally, serotonin molecules are produces on one side of a nerve synapse. The molecules then traverse the synapse and bind to the approp…
**MDMA is NOT an SRI.** It is a serotonin releaser. It reverses the action of your SERT, causing your neuronal synapse to flood with excess 5-HT. This is a big distinction for many reasons, which I will not get into at the moment. **Also, MDMA absolutely DOES affect your ability…
MDMA 'eases post-traumatic stress':
Replying to [deleted] · since you're a biochemist, can you answer me this? I heard 5-htp taken in pill form is bogus because the substance never breaks the blood brain barrier, and it actually has negativ…
No, that is incorrect. 5-HTP readily passes the blood brain barrier. However, it also readily converts to serotonin in your periphery by the enzyme aromatic L-amino acid decarboxylase. This is bad because serotonin, or 5-HT, cannot pass the blood brain barrier. This means that yo…
Engraved stone dating back 30,000 years found in China. Incisions imply possibility of counting or recording?
Replying to fjonk · > However, they were never exposed to differential calculus, the variety and extent of modern music and art, genetics, multiple languages, world travel, etc. Well, lots of people …
True. I was not speaking to averages. We have access to it now, so we have the ability for that stimulation. That does not mean that everyone will be exposed. My point was more that the ability for a human brain to develop is much more efficient now, given our knowledge and acces…
Engraved stone dating back 30,000 years found in China. Incisions imply possibility of counting or recording?
Replying to American_Pig · I think you are underestimating the scale of the skill set hunter gatherers need to have in order to survive. The average hunter gatherer from this period would need to be able to…
Thanks for the specific response. Perhaps I am understating the amount of neuronal activity that survival activities instigate. However, I was more speaking to the type of intelligence that modern societies value. We also are learning how to supplement for our brains to operate m…
Engraved stone dating back 30,000 years found in China. Incisions imply possibility of counting or recording?
Replying to oceanplexian · The OP said >They were still smart just didn't have all the accumulated knowledge we have today. That statement still holds true. Just because they didn't have access to accumu…
Yes, I completely agree. My statement was more of an addition with regards to an adult in that time period compared to one in ours. The regions of the brain associated with various activities like survival and problem solving may have had more neural connections than those of the…
Engraved stone dating back 30,000 years found in China. Incisions imply possibility of counting or recording?
Replying to [deleted] · [deleted]
That is what I thought, but did you not read the responses? I had to edit it due to a bunch of people jumping in saying it was incorrect or asking for sources. Nutrition and brain stimulation at specific times in adolescence, has drastic effects on the brain's structure as an adu…
Engraved stone dating back 30,000 years found in China. Incisions imply possibility of counting or recording?
Replying to [deleted] · The problem is you're unaware of where your thoughts are coming from. I can assure you they're from outdated colonialist anthropology.
My thoughts are coming from basic logic. The amount of nutrition our brains need to run at optimal efficiency for what we currently know, is very hard to achieve. The amino acids, antioxidants, and vitamins necessary to properly protect and operate the functions of long-term pote…
Engraved stone dating back 30,000 years found in China. Incisions imply possibility of counting or recording?
Replying to [deleted] · Yes! It is a huge stretch.
Then [here](http://www.uic.edu/classes/osci/osci590/6_1Paleopathology%20Disease%20in%20the%20Past.htm) is a better paper talking about the other periods. [Here](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1071659/) is one about early North Americans and malnutrition. [Here](http:…
Engraved stone dating back 30,000 years found in China. Incisions imply possibility of counting or recording?
Replying to [deleted] · It's your whole argument and the Social Darwinist lens clouding your thoughts that are the problem.
Social Darwinist lens? You have no idea where my thoughts are arising from. Basing your argument of an inference of my motivations for thoughts, shows that you are the one allowing bias to cloud your judgement.
Engraved stone dating back 30,000 years found in China. Incisions imply possibility of counting or recording?
Replying to [deleted] · You can't use a contemporary vulnerable poor community as a benchmark for what people may have been like in the Paleolithic. This is Social Darwinism at its worst. Also, their di…
Analysis of bones from ancient societies like the Mayans and Egyptians show anemia and malnutrition. Is it so much of a stretch to assume other ancient cultures shared this trait? http://news.discovery.com/history/mayan-bones-pre-historic-121114.html http://onlinelibrary.wiley.co…
Engraved stone dating back 30,000 years found in China. Incisions imply possibility of counting or recording?
Replying to shakes_mcjunkie · > development of neuronal connections is dependent on learning and usage. Since they weren't subject to nearly the same level of stimuli during their development, their intellectua…
Agreed. I was speaking to our definition of intelligence in modern society.