Comment · Wed, March 12, 2025 · ND Owner
Is ND done launching new products?
Original post in this thread
Experienced8 · 31 points
Title is self explanatory. No new products in 2025 yet...
Feels like the energy of the this subreddit has absolutely cratered lately.
What they were answering
HenryVonWilheimer · 2 points
Will you be releasing any of the Erinamax extracts you were testing out that would be standardized to a higher amount of Erinacine-A and/or other interesting erinacines?
Also wondering if you were ever able to source Evolvulus Alsinoides and if Catuaba is still in the works? Emiel hinted at beta testing some form of Catuaba in one of the podcasts. Exciting stuff on that list!
u/MisterYouAreSoDumb · ND Owner
Yes, we are still working on extracts of lion's mane mycelium. However, some beta testing we did make me pause, as I think the idea that extracts are better might not be true. Everyone parrots around that like it is fact, but we have actually found that removing some of these actives from the mycelial matrix lowers efficacy, not raises it. We think that is due to the fact that some of these bioactives are found in lipid delivery particles when in a non-extracted form, and extracting them from that does concentrate the bioactive, but might lower the bioavailability/bioaccessibility. We have been trying to figure out all the details, and then applying that to putting the extracts back into a delivery system that counteracts that. Our cell culture lab is a big part of that, because we will be able to culture human cells, like epithelial cells, and then measure how much actives actually absorb into the cells. Sartorius is at our facility today getting that set up. It will take us a bit to get going, but once we can actually measure these things in real human cells, we will be able to have a more data-driven formulation approach.
Catuaba is still in the works. It's just been a big challenge there, because everything on the market seems to be a different species. Even US labs are giving people passing COAs for products that we have shown are not the correct species. We had to get a botanist to go into the jungle in Brazil to get us raw plant, and then build our own BRMs after DNA analysis. However, we are close!