Comment · Fri, November 25, 2022 · ND Owner
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What they were answering
lewanay · 2 points
“Among the compounds tested in vitro, ebelin lactone showed binding affinity towards M1 (Ki = 0.45 μM) and 5-HT2A (4.21 μM) receptors”. This is quite interesting. So ebelin lactones effects are largely driven by its affinity for M1
u/MisterYouAreSoDumb · ND Owner
Yes, the M1 receptors are a big part of its effects. Both 5-HT2A and M1 seem to work synergistically for mood and memory.