Comment · Tue, June 7, 2022 · ND Owner
My optimum androgenic + dopaminergic stack (only 2 supps)
Original post in this thread
mrjasonbbc · 70 points
I've played with supps for some two decades and have arrived at a very interesting, very effective and very simple stack for increasing total androgen production and preserving an above normal feeling of dopaminergic tone. This is hands down my favorite stack and don't foresee stopping it anytime soon.
TL;DR: 200-300mg of ND cistanche combined with 100-200mg of agmatine sulphate right before bed and eat ample nutruent dense calories.
THE SCIENCE:
Cistanche targets multiple steroidogenic enzymes including StAR; increases spermatogenesis, testosterone, LH and progesterone; upregulates dopamine and downregulates cortisol; improves libido, erectile response and erectile latency in castrated rats; agonizes GABA; confers a broad range of anti aging and neuroprotective effects. Translation: Cistanche is the SHIT. No wonder it was Genghis Khan's herb of choice!
https://raypeatforum.com/community/threads/this-herb-is-stronger-than-tribulus.29991/
Agmatine provides broad neuroprotective, antidepressant, stress reducing benefits; inhibits GSK-3B, an enzyme that inhibits glycogen formation (FYI, cistanche also directly increases glycogen), prevents monoamine dysregulation when under stre…
What they were answering
Gabrielseifer · 3 points
This post has gotten a bit of attention since I first started following it, I'd love to hear what /u/MisterYouAreSoDumb, /u/Pretty-Chill, or someone else from ND chime in about what they think of this combo. Seems compelling to me.
u/MisterYouAreSoDumb · ND Owner
Just cistanche and agmatine? It's a solid combo. I have been telling everyone cistanche is way cooler than everyone realizes for a while. It has so many positive effects! We actually just published a cistanche blog. We haven't really promoted it yet, though. So only people browsing the site would have seen it.
https://nootropicsdepot.com/cistanche-more-than-just-a-testosterone-supplement
I also am a big fan of lower dose agmatine sulfate. I also use it at night. Adding in OmegaTAU at night will really round things out.