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Comment · Wed, June 8, 2022 · ND Owner

My optimum androgenic + dopaminergic stack (only 2 supps)

Original post in this thread

mrjasonbbc · 70 points

I've played with supps for some two decades and have arrived at a very interesting, very effective and very simple stack for increasing total androgen production and preserving an above normal feeling of dopaminergic tone. This is hands down my favorite stack and don't foresee stopping it anytime soon.

TL;DR: 200-300mg of ND cistanche combined with 100-200mg of agmatine sulphate right before bed and eat ample nutruent dense calories.

THE SCIENCE:

Cistanche targets multiple steroidogenic enzymes including StAR; increases spermatogenesis, testosterone, LH and progesterone; upregulates dopamine and downregulates cortisol; improves libido, erectile response and erectile latency in castrated rats; agonizes GABA; confers a broad range of anti aging and neuroprotective effects. Translation: Cistanche is the SHIT. No wonder it was Genghis Khan's herb of choice!

https://raypeatforum.com/community/threads/this-herb-is-stronger-than-tribulus.29991/

Agmatine provides broad neuroprotective, antidepressant, stress reducing benefits; inhibits GSK-3B, an enzyme that inhibits glycogen formation (FYI, cistanche also directly increases glycogen), prevents monoamine dysregulation when under stre…

What they were answering

mrjasonbbc · 3 points

WOW that is huge! Super interested in what your team finds! I am constantly impressed by the quality ND puts forth, but I'm more impressed by the novel, cutting edge inventory you can't find anywhere else. Keep it up!

u/MisterYouAreSoDumb · ND Owner

It's really the main thing that keeps us excited and moving forward. Bringing out basic supplements is boring. Pushing the standardization and lab side of things keeps us engaged and interested. When I shut Ceretropic down I feared that things would not be as fun as all the novel organic molecules and peptides. However, I was wrong. It's actually more fun working with plants and fungi, as the science is much more complex and the compounds are much more varied in nature. It's also cool doing our unique versions of things that seem basic, but actually surprise you in effects once you try them. There are also compounds that are biologically created that you just can't make synthetically. Our analytical and R&D lab is really the most fulfilling part of things. The rest just funds our ability to keep the lab going.

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