Comment · Wed, June 8, 2022 · ND Owner
My optimum androgenic + dopaminergic stack (only 2 supps)
Original post in this thread
mrjasonbbc · 70 points
I've played with supps for some two decades and have arrived at a very interesting, very effective and very simple stack for increasing total androgen production and preserving an above normal feeling of dopaminergic tone. This is hands down my favorite stack and don't foresee stopping it anytime soon.
TL;DR: 200-300mg of ND cistanche combined with 100-200mg of agmatine sulphate right before bed and eat ample nutruent dense calories.
THE SCIENCE:
Cistanche targets multiple steroidogenic enzymes including StAR; increases spermatogenesis, testosterone, LH and progesterone; upregulates dopamine and downregulates cortisol; improves libido, erectile response and erectile latency in castrated rats; agonizes GABA; confers a broad range of anti aging and neuroprotective effects. Translation: Cistanche is the SHIT. No wonder it was Genghis Khan's herb of choice!
https://raypeatforum.com/community/threads/this-herb-is-stronger-than-tribulus.29991/
Agmatine provides broad neuroprotective, antidepressant, stress reducing benefits; inhibits GSK-3B, an enzyme that inhibits glycogen formation (FYI, cistanche also directly increases glycogen), prevents monoamine dysregulation when under stre…
What they were answering
mrjasonbbc · 3 points
Right on! Cistanche has such a broad range of positive effects that it's really in a league of its own. I thought I saw somewhere here rumblings of a different cistanche extract in the works? If so, I AM EXCITE! 🤩
u/MisterYouAreSoDumb · ND Owner
Yep! We are working with CAMAG on another project helping them to write application notes for novel plant testing methods, so they are giving us their new HP-TLC mass spec add-on to use in our lab for a while. We are going to be using that to identify a bunch more active compounds in cistanche, tongkat, and a few other plants. We want to create a more comprehensive STAG for these things that have primary actives, but a bunch of others ones that are less understood. This will help us make our optimized tongkat and cistanche stacks for Natrium. Eurycomanone is only part of the story with tongkat, and echinacoside and acetoside are only part of the story for cistanche. We actually think there are a bunch of volatile organic compounds in cistanche, too. So we will be using our headspace GC to try and ID those, too!