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Comment · Thu, April 21, 2022 · 19 pts

This saffron is from Spain. We are working on other saffron extracts, but this is our first one that is more serotonin focused.

Comment · Thu, April 21, 2022 · 18 pts

I talked about it when we released OmegaTAU a bit. https://www.reddit.com/r/NootropicsDepot/comments/sjofmm/new_products_alert_omegatau_enhanced_uridine_dha/hwaix5y/ https://www.reddit.com/r/NootropicsDepot/comments/sj

Comment · Thu, April 21, 2022 · 18 pts

Yes, there are benefits to hitting multiple parts of the NAD+ cycle. This won't be our last NAD+ supplement, either. I think to get the absolute best effects, hitting various steps in the NAD+ cycle will prove to be adva

Comment · Thu, April 21, 2022 · 15 pts

The science is not super settled on it. We've done a LOT of testing on saffron now. We developed our own HP-TLC methods to tell exactly which part of the saffron plant was used in an extract, and what those components ar

Comment · Thu, April 21, 2022 · 15 pts

That's the plan! That's actually my personal favorite. I prefer saffron extracts with less serotonin effects. Those are just super rare. We decided to bring out a more balanced saffron first, as many people want the sero

Comment · Thu, April 21, 2022 · 8 pts

Right?!? It's such a super cool unique mood effect that is unlike any other HGW. We knew we found something special with this specific extract of the Epimedium brevicornum species!

Comment · Thu, April 21, 2022 · 8 pts

I have not personally stacked it with polygala, but I would imagine they would go well together. I will have to try the combo myself to see. ~~The same goes for black hoof. I haven't personally combined them yet, but I d

Comment · Thu, April 21, 2022 · 6 pts

A balanced mood-regulating effect. It also does have an appetite suppression effect. It's not super noticeable for me, as I fast all day anyway. However, it could be useful for people that have issues with hunger.

Comment · Thu, April 21, 2022 · 3 pts

¡Ole!

Comment · Fri, April 22, 2022 · 3 pts

Not enough to have a solid stance on it yet. Having a tocopherols and tocotrienols combo stack could be interesting, though.

Comment · Fri, April 22, 2022 · 4 pts

I personally gravitate away from the 5-HT effects as well. This is why we are still making my "perfect" saffron. I wanted to release this one first, though. It's more what most people are looking for in a saffron.

Comment · Sat, April 23, 2022 · 3 pts

It's mainly crocetin, which is the aglycone. It's not naturally high in most saffron.

Comment · Sat, April 23, 2022 · 3 pts

Wow, glad to hear that!

Comment · Sat, April 23, 2022 · 3 pts

It has immunomodulatory effects. A lot of that seems to be centered around lowering the immune response in autoimmune disorders. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055068/

Comment · Sat, April 23, 2022 · 2 pts

Super B12 and OmegaTAU (for the 5-MTHF)

Comment · Sat, April 23, 2022 · 4 pts

NMN should raise NAD+ more. However, your body is converting back and forth a lot, too. Supplementing NAD+ won't work. You need to take a precursor.

Comment · Sat, April 23, 2022 · 3 pts

Andrographis would be another one.

Comment · Mon, April 25, 2022 · 3 pts

I don't see why it couldn't. Usually I will take it midday, as part of PanaMAX, though.

Comment · Tue, April 26, 2022 · 2 pts

Sorry, I confused myself because we are working on the Vegan version. You are correct. Normal OmegaTAU does not have B6 in it.

Comment · Thu, April 28, 2022 · 2 pts

We have not found that to be the case. Nicotinamide riboside is very stable under normal conditions. You have to get over 115*C to have it start degrading. Also, it is stable in gastric fluid. Where it is not stable are

Comment · Thu, April 28, 2022 · 2 pts

No problem!

Comment · Fri, April 29, 2022 · 9 pts

A federal judge invalidated those patents back in November. https://www.prnewswire.com/news-releases/us-district-court-invalidates-dartmouth-patents-asserted-by-chromadex-301381257.html

Comment · Fri, April 29, 2022 · 3 pts

Because it is a pain in the ass to work with, and has very small doses. It stains everything, too.

Comment · Fri, April 29, 2022 · 3 pts

NMN and NR are both precursors. [Here is the NAD+ pathway](https://imgur.com/a/oCx4tA2).

Comment · Fri, April 29, 2022 · 9 pts

No problem! We actually went through something similar ourselves. It was not a patent, but a trademark. Same process, though. Someone trademarked "noopept" and the morons at the USPTO gave it to them... These people then

Comment · Fri, April 29, 2022 · 4 pts

That's how the patent was invalidated. Elysium was sued by Chromadex for patent infringement. Elysium fought back and argued the patents were not valid under 35 U.S.C. §101 and Supreme Court precedent. The federal judge

Comment · Thu, May 5, 2022 · 5 pts

We actually finally found a manufacturer in Australia making real liposomes of ginkgo, with SEM/TEM data to prove it. I think we could use them to make other liposomes as well. A tocotrienol liposome does sound interesti

Comment · Fri, June 17, 2022 · 5 pts

The other saffron? That's taking more time. It's harder than it sounds. The saffron market is tough, because most of it is going to culinary use. Not a lot of people are doing supplements with it; especially standardized