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Comment · Sun, October 24, 2021 · ND Owner

Reddit AMA | In-House Lab Edition

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NootropicsDepotGuru · 77 points

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We are very excited to announce that Nootropics Depot will be conducting its first-ever Reddit AMA (Ask Me Anything), which is a semi-live Q&A session, about our In-House Analytical Laboratory and we would love for you to join us! See below for full details and get your question(s) ready. We hope to see you there!

WHEN

STARTS: October 20th | 9am AZ MST

ENDS: October 22nd | 9am AZ M…

What they were answering

labratdream · 1 points

1. Do you test herbal extract for mold ?
2. Do you use microsieves to exclude the possibility of parasite eggs contamination ?
3. How do you test for common solvents and residues ?
4. Have you ever considered to improve existing product selection by offering for example r-phenylpiracetam, pramiracetam sulfate , orginal deanol ( dmae p-acetamidobenzoate )

u/MisterYouAreSoDumb · ND Owner

1) We test for water activity in every batch, which can detect mold along with bacteria. We don't specifically send off for mold cultures unless we think there is an issue, though.

2) I don't think anyone in the world does that. It's not something that is a likely QC issue.

3) We test via headspace GC-FID. We spent almost a year developing our GC methods to test for residual solvents. How this process works is a sample is dissolved in water, heated in a small oven, and the gas that evolves is automatically injected into the instrument. It then gets separated based on its boiling point, and eventually burns up in the Flame Ionization Detector, or FID. Essentially, we are exposing the sample to a hydrogen flame, then detecting the ions formed during combustion. From this process a chromatogram is generated. When calibrated properly, the amount of each residual solvent present can be identified and quantified to extreme precision. This instrument measures solvents in the parts per billion range (ppb) and is accurately and precisely calibrated. Needless to say, this instrument and method is vigorously validated using known reference standards, which is how we can get the precision.

4) Yes, we have worked on some of those. We will be bringing out improved versions of things we already sell as time goes on. Our plan is to do those syntheses ourselves in our own lab, so we can control the process in greater detail. We can also do smaller batches that are difficult to talk larger labs into taking on.

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